DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6967 and mov10l1

DIOPT Version :9

Sequence 1:	NP_611185.3	Gene:	CG6967 / 36922	FlyBaseID:	FBgn0034187	Length:	764	Species:	Drosophila melanogaster
Sequence 2:	NP_001072624.1	Gene:	mov10l1 / 780080	XenbaseID:	XB-GENE-1217451	Length:	1244	Species:	Xenopus tropicalis

Alignment Length:	755	Identity:	211/755 - (27%)
Similarity:	319/755 - (42%)	Gaps:	194/755 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LPYYPPSNEMIEANTNQ-DLSANNSVFGDFMKTKRLEFYNVCSVMQTLLTIDDLSNMELYAQLIQ 67
            ||.||..:.:.:....: |:.|.....|:.     |...|....|.|||.::|          |.
Frog   559 LPLYPIPDRLRKCTEQKMDILALEPCLGEV-----LTLSNYRKRMSTLLWLED----------IH 608

  Fly    68 SDVPVQRVSKLTYKITFKSTPVNAEDFVAPNLDQVVLVPKASLLASPLPKQLVLALLPHPHEDLE 132
            :::.:|..|                      |..|.|..:...|...:|             .:.
Frog   609 AEMEIQEFS----------------------LSGVCLQKRGGFLLLEVP-------------GIA 638

  Fly   133 PGDPMLRHVASVDKVSSTTVHVRFSRKHKAVLSGQRFYAI---IRSRRLTIR--------YMYRA 186
            .|.|.|.   ..|||        |.:..:...:..:|..:   |....:|:|        |.:..
Frog   639 EGRPFLN---QGDKV--------FLKYQELTTTAIQFVGLIVEIHEEEITLRVNEELEQSYKFEP 692

  Fly   187 LN----------------LLQESPLVRRYLFP------FPSWLTQLVDNSQIKVCCDGHLPNWMQ 229
            ::                :.|...|.::.|||      .|...::  |.|:|..........:.:
Frog   693 MDVEFVVNRVTSRRCQFAVEQAEHLGQKVLFPDTVELQSPQVASR--DTSEIDCPEKKEKTGYQE 755

  Fly   230 GRPQEP----------------ATPTSLSLLNSTIYS---------NAEQLEAVQRIVAGPSTQG 269
            .....|                ||.||.....|.:..         |..|..||:||:.|.....
Frog   756 TNQSNPTSRGKNAVYMSDMVTVATQTSTKGSGSPVKKKGQFFNNLLNNHQKLAVKRILGGECRPT 820

  Fly   270 PYILFGPPGTGKTTTIVEAILQLRLQQPQSRILVTAGSNSACDTIALKLCEYIESNIRLQEHFAQ 334
            |||||||||||||.||:|||||:....|.|||||.|.||||.|.:.|:|            |.:.
Frog   821 PYILFGPPGTGKTVTIIEAILQIYYALPDSRILVCAPSNSAADLVCLRL------------HQSN 873

  Fly   335 QKLPEPDHQLIRVYSRSIYEKGFASVPSLLLKNSNC--SKSIYDHI-----------KASRIVKY 386
            |..|   ..::||                   |:.|  .:::.|.:           ||||   :
Frog   874 QLEP---GSMVRV-------------------NATCRLEETVCDAVRPYCGPGEDIRKASR---F 913

  Fly   387 GIIVATLCTVARLVTDTLGRYNFFTHIFIDEAGASTEPEALIGIMGIKQTADCHVILSGDHKQLG 451
            .||::| |:.|.:......|...|||:|:||||.::|||.||. :|:.......:||:||..|||
Frog   914 RIIIST-CSSAGMFYQIGLRVGHFTHVFVDEAGQASEPECLIP-LGLISEVTGQIILAGDPMQLG 976

  Fly   452 AVIKSNRAASLGLSRSLMERLLQSDCYKSDEN-----GNYDRNRQMRLCRNYRSHPQIVRLFNEL 511
            .:|||..:.:.||:.|.:|||:....|..||.     |||:.....:|.:|||||..::.|.::|
Frog   977 PIIKSRVSLAYGLNVSFLERLMARPLYLRDEESYGACGNYNPLLITKLMKNYRSHAALLHLPSKL 1041

  Fly   512 YYNGELKAQAPAMDVNLAANWSVLTNPQFPIIFQATHGVTNREQNSTSSYNNLEA----EVICWY 572
            :|:.||:..|....||....|..|.:..||:||....|...||.::.|.:|..||    ...|..
Frog  1042 FYHKELEVCADPAVVNKLLRWDKLPHKGFPLIFHGVRGTEMREGSNPSWFNPSEAVQAMRYCCVL 1106

  Fly   573 VKRLINDRVVGQEDVGIVAPYTAQGKLVTKLLQSKGYPNVEVGSVETYQGREKTIIIASLVKSFT 637
            .|.:...  |..:|:|::.||..|.:.:..||::....:::|||||.:||:|..:||.|:|:|..
Frog  1107 AKHVTTS--VSAKDIGVITPYRKQVEKIRTLLRTADLSDIKVGSVEEFQGQEFLVIIISMVRSCE 1169

  Fly   638 N---------MGFMCNPRRVNVLLSRAKALLILVGNPVTL 668
            :         :||:|:|:|.||.::|.|||||::|||..|
Frog  1170 DSLHEDSRHLLGFLCSPKRFNVAITRPKALLIVLGNPHVL 1209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6967	NP_611185.3	AAA_11	251..456	CDD:289831	81/217 (37%)
		AAA_19	256..323	CDD:289986	39/66 (59%)
		UvrD_C_2	464..665	CDD:304668	75/218 (34%)
mov10l1	NP_001072624.1	S1-like	36..>73	CDD:291136
		S1-like	182..234	CDD:291136
		AAA_11	801..982	CDD:289831	82/219 (37%)
		P-loop_NTPase	801..>978	CDD:304359	80/215 (37%)
		DNA2	<914..1213	CDD:224037	109/300 (36%)
		AAA_12	989..1206	CDD:289832	75/218 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D148890at33208
OrthoFinder	1	1.000	-	-		FOG0000219
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10887
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R9180
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.050