Protein Alignment Mov10 and Upf1

DIOPT Version :10

• Sequence 1: NP_611185.3
• Gene: Mov10 / 36922
• FlyBaseID: FBgn0034187
• Length: 764
• Species: Drosophila melanogaster
• Sequence 2: XP_063131800.1
• Gene: Upf1 / 684558
• RGDID: 1589127
• Length: 1124
• Species: Rattus norvegicus
• Alignment Length: 450
• Identity: 137/450 - (30%)
• Similarity: 205/450 - (45%)
• Gaps: 74/450 - (16%)

  Fly   251 NAEQLEAVQRIVAGPSTQGPYILFGPPGTGKTTTIVEAILQLRLQQPQSRILVTAGSNSACDTIA 315
            |..|:.||:.::..|.:    ::.||||||||.|....:..| .:|....:||.|.||.|.|.:.
  Rat   478 NHSQVYAVKTVLQRPLS----LIQGPPGTGKTVTSATIVYHL-ARQGNGPVLVCAPSNIAVDQLT 537

  Fly   316 LKLCEYIESNIRLQEHFAQQKLPEPD-----HQLIRVYSRSIYEKGFASVPSL----LLKN---- 367
            .|:.:.....:||... :::.:..|.     |..||         ...|:|.|    .||:
  Rat   538 EKIHQTGLKVVRLCAK-SREAIDSPVSFLALHNQIR---------NMDSMPELQKLQQLKDETGE 592

  Fly   368 -SNCSKSIYDHIK--ASR--IVKYGIIVATLCTVARLVTDTLGRYNFFTHIFIDEAGASTEPEAL 427
             |:..:..|..:|  |.|  ::...:|   .||........|.:.. |..|.|||:..:||||.:
  Rat   593 LSSADEKRYRALKRTAERELLMNADVI---CCTCVGAGDPRLAKMQ-FRSILIDESTQATEPECM 653

  Fly   428 IG-IMGIKQTADCHVILSGDHKQLGAVIKSNRAASLGLSRSLMERLLQSDCYKSDENGNYDRNRQ 491
            :. ::|.||     :||.|||.|||.|:...:||..|||:||.|||:....            |.
  Rat   654 VPVVLGAKQ-----LILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGI------------RP 701

  Fly   492 MRLCRNYRSHPQIVRLFNELYYNGELKAQAPAMD---VNLAANWSVLTNPQFPIIFQATHGVTNR 553
            :||...||.||.:....:.::|.|.|:....|.|   ......|   ..|..|:.|..|.|....
  Rat   702 IRLQVQYRMHPALSAFPSNIFYEGSLQNGVTAADRVKKGFDFQW---PQPDKPMFFYVTQGQEEI 763

  Fly   554 EQNSTSSYNNLEAEVICWYVKRLINDRVVG--QEDVGIVAPYTAQGKLVTKLLQSKG------YP 610
            ..:.||..|..||..:.....:|:.   .|  .:.:||:.||..|...:.:.:|..|      |.
  Rat   764 ASSGTSYLNRTEAANVEKITTKLLK---AGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQ 825

  Fly   611 NVEVGSVETYQGREKTIIIASLVKS--FTNMGFMCNPRRVNVLLSRAKALLILVGNPVTL 668
            .||:.||:.:|||||..||.|.|::  ...:||:.:|||:||.|:||:..:|:||||..|
  Rat   826 EVEIASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKAL 885

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mov10	NP_611185.3	DEXXQc_Helz-like	251..499	CDD:350796	78/266 (29%)
		DNA2	<388..684	CDD:440729	96/294 (33%)
Upf1	XP_063131800.1	None