DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6967 and mov10b.1

DIOPT Version :9

Sequence 1:	NP_611185.3	Gene:	CG6967 / 36922	FlyBaseID:	FBgn0034187	Length:	764	Species:	Drosophila melanogaster
Sequence 2:	NP_001037807.2	Gene:	mov10b.1 / 556024	ZFINID:	ZDB-GENE-030131-9089	Length:	1013	Species:	Danio rerio

Alignment Length:	787	Identity:	232/787 - (29%)
Similarity:	365/787 - (46%)	Gaps:	159/787 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 PYYP-------PSNEMIEANTNQDLSANNSVFGDFMK-TKRLEFYNVCSVMQTLLTI-------- 53
            |:.|       |....|:.....:.|:.|     |:| ...|:.||..|....|:.:
Zfish   288 PFRPKRLDTNQPMKWSIDEGFKPESSSQN-----FLKFVVPLDNYNCPSYTSALIEVLKGNRSSG 347

  Fly    54 -----------DDLS--------NMELYAQLIQSDVPVQRVSKLTYKITFKSTPVNAEDFVAPNL 99
                       .|||        ::.||.:..|..:.::|.:|             .:..:..:.
Zfish   348 KQLQEHQLTLESDLSFNNYMDRFDLLLYLEEDQMRMDIKRYNK-------------KDVSMVRDR 399

  Fly   100 DQVVLVPKASLLASPLPKQLVLA---LLPHPHEDLEPGDPMLRHVASVDKVSSTTVHVRFSRK-H 160
            |:.:||.:...::...|.  ||.   ||....|:|:..: :.::...|.:|....|.:.||:: .
Zfish   400 DKKLLVLELPGVSENRPS--VLRGDHLLLTKSEELQNSN-VTKYKGYVHRVELDQVKLGFSKRLL 461

  Fly   161 KAVLSGQRFYAIIRSRRLTIRYMYRALNLLQESPLVRRYLFPFPSWLTQLVDNSQIKVCCDGHLP 225
            :..:...:|.......||.:|..:||::::.:..| :..|||..|
Zfish   462 ERFIDNMKFSVEFTINRLPLRLQHRAVHMVVQHHL-KDVLFPVAS-------------------- 505

  Fly   226 NWMQGRPQEPATPTSLSLLNSTIYSNAEQLEAVQRIVAGPSTQGPYILFGPPGTGKTTTIVEAIL 290
                 |...|.:|::|.|.:..:..|.||..||..||||.|...||::|||||||||.||||||.
Zfish   506 -----RRLNPVSPSALRLFDQKLEKNPEQKTAVCNIVAGTSKPAPYLVFGPPGTGKTVTIVEAIK 565

  Fly   291 QLRLQQPQSRILVTAGSNSACDTIALKL--CEYIESNIRLQEHFAQQKLPEPDHQLIRVYSRSIY 353
            |:......:|||..|.||||.|.:..||  .:::::                 ..:.|:|:.|..
Zfish   566 QVEKNTGGARILACAPSNSAADQLGEKLITSQHVDA-----------------RNIYRIYASSRN 613

  Fly   354 EKGFASVPSLLLKNSNC-SKSIYDHIKASRIVKYGIIVATLCTVARLVTDTLGRY--NFFTHIFI 415
            .|   .:|.:|..|||. .::|....|.. ::.|.|:|.||.|..|||:   |.:  ..|:|||:
Zfish   614 PK---EIPKVLENNSNVEGENIIFPCKED-LMPYKIVVCTLVTAGRLVS---GGFPVGHFSHIFV 671

  Fly   416 DEAGASTEPEALIGIMGIKQTADCHVILSGDHKQLGAVIKSNRAASLGLSRSLMERLL-QSDCYK 479
            ||||.:.|||.:|.:.|:.......::|:||.||||.:::|..|...||..||:|||: |::.|:
Zfish   672 DEAGHAVEPEIVISVAGLLNAETGQLVLAGDPKQLGPILRSPFAIKYGLGLSLLERLMTQNELYQ 736

  Fly   480 SDENGNYDRNRQMRLCRNYRSHPQIVRLFNELYYNGELKAQAPAMDVNLAANWSVLTNPQFPIIF 544
            ..:.| :|.....:|.:||||||.|:::.|||:|:.||||.|..:.......|..|....||:||
Zfish   737 KGDTG-FDNRYVTKLLQNYRSHPSILKVPNELFYDNELKACADEISSRQYCTWEHLPKRGFPVIF 800

  Fly   545 QATHGVTNREQNSTSSYNNLEAEVICWYVKRLINDRV------VGQEDVGIVAPYTAQGKLVTKL 603
            ....|...||..|.|.:|..|.:.|..|:|:|:..:.      :..:|:||:|||..|   |.|:
Zfish   801 HGVVGKDERESTSPSFFNTSEIDKIMDYLKKLLLTQAKKGIAKISPKDIGIIAPYRKQ---VEKI 862

  Fly   604 LQS----------KGYPNVEVGSVETYQGREKTIIIASLVKSFT---------NMGFMCNPRRVN 649
            .|:          .|...::|||||.:||:|:.:||.|.|:|..         |:||:.|.:|.|
Zfish   863 RQAIKIHRELKSLSGIEELKVGSVEEFQGQERKVIIVSTVRSSKEHIILDDKFNIGFLKNEKRFN 927

  Fly   650 VLLSRAKALLILVGNPVTLRHHSDFKFVINECKKHGTYL------LKKRD--------SGQRPHI 700
            |.::|||||||:||||:.||....:...:|.|.:...|.      |::.|        ...|..|
Zfish   928 VAVTRAKALLIMVGNPIILRTDEIWGRFMNYCIQERGYTGYDITHLEETDVIAERLLSLNIRQEI 992

  Fly   701 LIKADES 707
            .::.:||
Zfish   993 TVETEES 999

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6967	NP_611185.3	AAA_11	251..456	CDD:289831	80/209 (38%)
		AAA_19	256..323	CDD:289986	36/68 (53%)
		UvrD_C_2	464..665	CDD:304668	84/226 (37%)
mov10b.1	NP_001037807.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	91..129
		P-loop_NTPase	526..>734	CDD:304359	90/231 (39%)
		AAA_11	526..713	CDD:289831	80/210 (38%)
		DEAG box	672..675		2/2 (100%)
		AAA_12	720..943	CDD:289832	84/226 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	151	1.000	Domainoid score	I4307
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D148890at33208
OrthoFinder	1	1.000	-	-		FOG0000219
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R9180
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.810