Protein Alignment Mov10 and helz2c

DIOPT Version :10

• Sequence 1: NP_611185.3
• Gene: Mov10 / 36922
• FlyBaseID: FBgn0034187
• Length: 764
• Species: Drosophila melanogaster
• Sequence 2: NP_001428512.1
• Gene: helz2c / 552926
• ZFINID: ZDB-GENE-050508-3
• Length: 1546
• Species: Danio rerio
• Alignment Length: 616
• Identity: 144/616 - (23%)
• Similarity: 235/616 - (38%)
• Gaps: 149/616 - (24%)

  Fly   143 SVDKVSSTTVHVRFSRKHKAVL--------SGQRFYAIIRSRRLTIRYMYR---ALNLLQESPLV 196
            |..|.::|...:.|...|:::.        .|.:|...:..::  |.|:.|   ..||.:.:.||
Zfish   935 SKKKDANTKGRINFKITHRSMTYIPARIFNKGTKFTIEVIPKK--IPYLLREQAVANLKRANNLV 997

  Fly   197 RRYLFPFPSWLTQLVDNSQIKVCCDGHLPNWMQGRPQEPATPTSL-----SLLNSTIYSNAEQLE 256
            :.            |...::::..|..|.|            .||     ||...|:  |..|.:
Zfish   998 KS------------VATGKLELNDDADLRN------------ISLYDVDKSLNLPTL--NMSQKK 1036

  Fly   257 AVQRIVAGPSTQGPYILFGPPGTGKTTTIVEAILQLRLQ-----------------QPQSR--IL 302
            ||:..:..|.|    ::.||||||||...:..:.|...:                 .|..:  ||
Zfish  1037 AVKEAMKKPFT----VIQGPPGTGKTVVGIHIVFQFFKKNKDFMTSFKPNHTNPDGNPPKKPAIL 1097

  Fly   303 VTAGSNSACDTIA---LKL----------CEYIE--------SNIRLQEHFAQQKLPEPD-HQLI 345
            ....||.:.|.:|   |||          |:.:|        |.::|.....:.:.|:.: ..:.
Zfish  1098 YCGPSNKSVDIVAEQLLKLSGVLKPLRIYCDQMEMREFPYTGSELKLCRRSLRDEKPKEELRDIT 1162

  Fly   346 RVYSRSIYEKGFASVPSLLLKNSNCS-----KSIYDHIKASRIVKYGIIVATLCTVARLVTDTLG 405
            .:|.....|..|:.....|.||.:..     :.:........|.||.::   |||.:..:...|.
Zfish  1163 LMYLVRKPENPFSEEIKALEKNLSVDQIDNYRKLLKKANQHEIEKYDVV---LCTCSSALKPELR 1224

  Fly   406 RYNFFTHIFIDEAGASTEPEALIGIMGIKQTADCHVILSGDHKQLGAVIKSNRAASLGLSRSLME 470
            ....|..|.|||...:|||||.|.::.....   .::|.|||:|:..:::.....:.|:.:||.|
Zfish  1225 EVMDFRQILIDECAMATEPEAFIPLVSHNPQ---QIVLLGDHQQIRPIVQCGHVKNKGMEKSLFE 1286

  Fly   471 RLLQSDCYKSDENGNYDRNRQMRLCRNYRSHPQIVRLFNELYYNGELKAQA---PAMDVNLAANW 532
            |      |....|         .|...||.|.:|....::.:|:|:||..|   |...:|.:...
Zfish  1287 R------YMDLAN---------MLDTQYRMHAEICSFPSDEFYDGKLKTGAERGPCCLLNKSKEP 1336

  Fly   533 SVLTNPQFPIIFQATHG------VTNREQNSTSSYNNLEAEVICWYVKRLINDRVVGQEDVGIVA 591
            :.:       :|....|      |:..:.|..|..|..|||........||....|..|.:.|:.
Zfish  1337 TAM-------LFGHIEGKEVSLVVSTEKGNENSMANTEEAEQAVCVADLLIKQSGVSPEHIAILT 1394

  Fly   592 PYTAQGKLVTKLLQSKGYPNVEVGSVETYQGREKTIIIASLVKSFT------------------N 638
            ||.||...:...|:.|...||.|.:|...||.|...:|.|.|:|.:                  .
Zfish  1395 PYNAQVSEIKMTLEKKNVRNVTVCTVMKSQGSEWPYVIVSTVRSCSTSDIQAYRVRPHKAWLGKR 1459

  Fly   639 MGFMCNPRRVNVLLSRAKALLILVGNPVTLR 669
            :||:.:..:|||.::||:..|.::||...||
Zfish  1460 LGFVTDANQVNVAITRAQDGLCILGNSDLLR 1490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mov10	NP_611185.3	DEXXQc_Helz-like	251..499	CDD:350796	67/293 (23%)
		DNA2	<388..684	CDD:440729	82/309 (27%)
helz2c	NP_001428512.1	None