Protein Alignment Mov10 and Helz

DIOPT Version :10

• Sequence 1: NP_611185.3
• Gene: Mov10 / 36922
• FlyBaseID: FBgn0034187
• Length: 764
• Species: Drosophila melanogaster
• Sequence 2: NP_648725.2
• Gene: Helz / 39613
• FlyBaseID: FBgn0036451
• Length: 2103
• Species: Drosophila melanogaster
• Alignment Length: 708
• Identity: 183/708 - (25%)
• Similarity: 310/708 - (43%)
• Gaps: 141/708 - (19%)

  Fly    36 KRLEFYNVCSVMQTLLTIDDLSNMELYAQLIQSDVPVQRVSKLTYKITFKSTPV-----NAEDFV 95
            |||...|..|.:..||::::::.   |.|:.:.:|.    ::||....:..||.     .|:..:
  Fly   611 KRLTQNNYRSRIHELLSVEEIAR---YEQIARYNVR----TRLTVASNYILTPAGMATSTAKYSL 668

  Fly    96 APNLDQVVLVPKASLLASPLPKQLVLA-----LLPHPHEDLEPGDPMLRHV--ASVDKVSSTTVH 153
            |..|..::.:.| .:.....|.:|:|:     .:..|.:.....||..|.|  |.::......::
  Fly   669 AGELFALMRLGK-DISEDTSPGRLILSNCSSVYISKPEDPDSKADPTKRAVYEALIEDKGKNVIY 732

  Fly   154 VRFSRKHKAVLSGQRFYAI-----IRSRRLTIRYMYRALNLLQESPLVRRYLFPFPSWLTQLVDN 213
            ::.|.|....::.|....:     .:..|:.....:.|::.:.:..|:      ||:  |:|
  Fly   733 LKLSAKCVEAMALQADTELEVDIQFQLNRMPYCEWHNAVDKITDFRLI------FPA--TEL--- 786

  Fly   214 SQIKVCCDGHLPNWMQGRPQEPATPTSLSLLNSTIYSNAEQLEAVQRIVAGPSTQ-GPYILFGPP 277
                             .|..|.||......:.....||:|.|||..|....|.: .|.:|.||.
  Fly   787 -----------------EPSIPWTPKKQWADSCEPKLNAKQREAVNAITTALSIKLPPILLIGPF 834

  Fly   278 GTGKTTTIVEAILQLRLQQPQSRILVTAGSNSACDTIALKLCEYIESNIRLQEHFAQQKLPEPDH 342
            |||||.|:.:||.|| |.||:::||:...||||.|   |.:.||:...|   |...::..|
  Fly   835 GTGKTYTLAQAIKQL-LTQPEAKILICTHSNSAAD---LYIKEYLHPWI---EEGLKEATP---- 888

  Fly   343 QLIRVYSRSIYEKGFASVPSLLLKNSNCSKSIYDHIK--ASRIVKYGIIVATLCTVARLVTDTLG 405
              :|||    |.|.:::..:.:::....:..:.:.::  ...|:::.|:|.||.....|.|..|.
  Fly   889 --LRVY----YHKRWSATVNGVVQKYCITDGVGNFLRPTVEDIMRHRIVVVTLSISMELATLGLP 947

  Fly   406 RYNFFTHIFIDEAGASTEPEALIGIMGIKQTAD-CHVILSGDHKQLGAVIKSNRAASLGLSRSLM 469
            : ..|||||:|||..:.|.||   ||.:....| ..::|:|||.|:...:.|..|....|..||:
  Fly   948 K-GLFTHIFLDEAAQAMECEA---IMPLALANDSTRIVLAGDHMQMSPELFSAFAKERKLHISLL 1008

  Fly   470 ERLLQSDCYKSDENGNYDRNRQMRLCRNYRSHPQIVRLFNELYYNGELKA--QAPAMDVNLAANW 532
            |||.  |.|.|    |:.  .::.||.|||:|..|:|..:||:|..:|.|  :.|..|
  Fly  1009 ERLY--DHYPS----NFP--CKILLCENYRAHEAIIRFTSELFYEQKLVASGKQPRHD------- 1058

  Fly   533 SVLTNPQFPIIFQATHGVTNREQNSTSSYNNLEAEVICWYVKRL----------INDRVVGQEDV 587
                 ..:|:.|..|.|...:::|||:.|||.|...:...|..|          :||     ..:
  Fly  1059 -----RFYPLTFFTTRGEDVQDKNSTAFYNNAEVYEVVERVSELRKRWPSAWGKLND-----TSI 1113

  Fly   588 GIVAPYTAQGKLVTKLLQSKGYPNVEVGSVETYQGREKTIIIASLVK---------------SFT 637
            ||:.||:.|...:...|:.:....:.|..|...||::...:..|.|:               |.|
  Fly  1114 GIMTPYSDQVFRIRSELRKRRMGGISVERVLNVQGKQFRAVFLSTVRTRRTCMPQGSAPGSASTT 1178

  Fly   638 NM-------GFMCNPRRVNVLLSRAKALLILVGNPVTL----RHHSDFKFVINECKKH 684
            ::       ||:.|.:.:|..::||::|:.:||:||.|    |....::..|..|.:|
  Fly  1179 SIGDADADYGFLSNSKLLNTAITRAQSLVAVVGDPVALCSIGRCRKVWERFIEICDEH 1236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mov10	NP_611185.3	DEXXQc_Helz-like	251..499	CDD:350796	85/251 (34%)
		DNA2	<388..684	CDD:440729	97/334 (29%)
Helz	NP_648725.2	zf-CCCH	329..353	CDD:459885
		DEXXQc_HELZ	805..1030	CDD:350835	85/253 (34%)
		DNA2	<925..1236	CDD:440729	98/339 (29%)