DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6967 and Mov10l1

DIOPT Version :9

Sequence 1:	NP_611185.3	Gene:	CG6967 / 36922	FlyBaseID:	FBgn0034187	Length:	764	Species:	Drosophila melanogaster
Sequence 2:	XP_017450774.2	Gene:	Mov10l1 / 300141	RGDID:	1304735	Length:	1291	Species:	Rattus norvegicus

Alignment Length:	471	Identity:	162/471 - (34%)
Similarity:	243/471 - (51%)	Gaps:	71/471 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   251 NAEQLEAVQRIVAGPSTQGPYILFGPPGTGKTTTIVEAILQLRLQQPQSRILVTAGSNSACDTIA 315
            |..|..||:||::|.....|||||||||||||.||:||:||:....|.|||||.|.||||.|.:.
  Rat   844 NENQKLAVRRILSGDCRPLPYILFGPPGTGKTVTIIEAVLQVHYALPDSRILVCAPSNSAADLVC 908

  Fly   316 LKLCEYIESNIRLQEHFAQQKLPEPDHQLIRVYSRSIYEKGFASVPSLLLKNSNC--SKSIYDHI 378
            |:|.|              .|:.:| ..::||                   |:.|  .::|.:.|
  Rat   909 LRLHE--------------SKVLKP-AAMVRV-------------------NATCRFEETIIEAI 939

  Fly   379 KAS--------RIVKYGIIVATLCTVARLVTDTLGRYNFFTHIFIDEAGASTEPEALIGIMGIKQ 435
            |..        |..::.||:.| |:.|.|......|..:|||:|:||||.::|||.||. :|:..
  Rat   940 KPYCRDGEDIWRASRFRIIITT-CSSAGLFYQIGVRVGYFTHVFVDEAGQASEPECLIP-LGLIS 1002

  Fly   436 TADCHVILSGDHKQLGAVIKSNRAASLGLSRSLMERLLQSDCYKSDEN-----GNYD-------- 487
            ..:..::|:||..|||.||||..|.:.||:.|::|||:....|..|||     |.|:
  Rat  1003 DINGQIVLAGDPMQLGPVIKSRLAMAYGLNVSMLERLMSRPAYLRDENAFGACGAYNPLLPLPAS 1067

  Fly   488 RNRQMRLCRNYRSHPQIVRLFNELYYNGELKAQAPAMDVNLAANWSVLTNPQFPIIFQATHGVTN 552
            ..:..:|.:|||||..::.|.:.|:|:.||:..|....|.....|..|....||:||....|...
  Rat  1068 SPQVTKLVKNYRSHSALLALPSRLFYHRELEVCADPKVVTSLLGWEKLPRKGFPLIFHGVRGNEA 1132

  Fly   553 REQNSTSSYNNLEAEVI---CWYVKRLINDRVVGQEDVGIVAPYTAQGKLVTKLLQSKGYPNVEV 614
            ||..|.|.::..||..:   |..:.|.::.: |..:|:|::.||..|.:.:..||::....:::|
  Rat  1133 REGRSPSWFSPAEAVQVMRYCCLLARNVSSQ-VSSKDIGVITPYRKQVEKIKILLRNVDLTDIKV 1196

  Fly   615 GSVETYQGREKTIIIASLVKSFTN--------MGFMCNPRRVNVLLSRAKALLILVGNPVTLRHH 671
            ||||.:||:|..:|:.|.|:|..:        :||:.|.:|.||.::|.|||||::|||..|...
  Rat  1197 GSVEEFQGQEYLVIVISTVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPKALLIVLGNPHVLVRD 1261

  Fly   672 SDFKFVINECKKHGTY 687
            ..|..::.....:|.|
  Rat  1262 PCFGALLEYSVTNGVY 1277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6967	NP_611185.3	AAA_11	251..456	CDD:289831	80/214 (37%)
		AAA_19	256..323	CDD:289986	39/66 (59%)
		UvrD_C_2	464..665	CDD:304668	72/224 (32%)
Mov10l1	XP_017450774.2	PRK08581	657..>833	CDD:236304
		DEXXQc_Mov10L1	842..1079	CDD:350836	97/270 (36%)
		SF1_C_Upf1	1080..1270	CDD:350195	61/190 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335125
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D148890at33208
OrthoFinder	1	1.000	-	-		FOG0000219
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10887
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.950