Protein Alignment Mov10 and Helz2

DIOPT Version :10

• Sequence 1: NP_611185.3
• Gene: Mov10 / 36922
• FlyBaseID: FBgn0034187
• Length: 764
• Species: Drosophila melanogaster
• Sequence 2: NP_001292205.1
• Gene: Helz2 / 296474
• RGDID: 1306056
• Length: 2944
• Species: Rattus norvegicus
• Alignment Length: 523
• Identity: 137/523 - (26%)
• Similarity: 220/523 - (42%)
• Gaps: 95/523 - (18%)

  Fly   228 MQGRPQEPATPTSLSLLNSTIYSNAEQLEAVQRIVAGPSTQ----GPYILF-GPPGTGKTTTIVE 287
            :||.|....|.....::.....||.||:..    .:.||.:    ||.:|: ||  :.|:..::.
  Rat  2466 IQGPPGTGKTVVGFHIVYWFHRSNQEQMPT----GSSPSEEEKLGGPCVLYCGP--SNKSVDVLG 2524

  Fly   288 AILQLRLQQPQSRILVTAGSNSACDTIAL----------KLCEYIESNIRLQE---HFAQQKLPE 339
            .:| || ::.:.|.|...|..:......|          |:.:....|..|:.   |...::.|.
  Rat  2525 GLL-LR-KKTEMRPLRVYGEQAEATEFPLPGVSNRSLFGKISQEGRPNQSLRSITLHHRIRQAPN 2587

  Fly   340 PDHQLIRVYSRSIYEKGFASVPSLLLKNSNCSKSIYDHIKASRIVKYGIIVATLCTVARLVTDTL 404
            |....||.:...:.|....|...||:......|:     :...:.::.:|   |||.:...:.:|
  Rat  2588 PYAAEIRKFDAQLREGKIFSKDDLLVYRRVLGKA-----RKYELERHSVI---LCTCSCAASGSL 2644

  Fly   405 GRYNFFTHIFIDEAGASTEPEALIGIMGIKQTADCHVILSGDHKQLGAVIKSNRAASLGLSRSLM 469
            ...| ...|.|||||.:||||.||.::...:|.  .|:|.||||||..|:|:.:..:||:.|||.
  Rat  2645 KALN-VRQILIDEAGMATEPETLIPLVCFSKTE--KVVLLGDHKQLRPVVKNEQLRNLGMDRSLF 2706

  Fly   470 ERLLQSDCYKSDENGNYDRNRQMRLCRNYRSHPQIVRLFNELYYNGELKAQAPAMDVNLAANWSV 534
            ||              |.|:..| |...||.|..|....:..:|.|:||            .||.
  Rat  2707 ER--------------YHRDAIM-LDTQYRMHKDICSFPSMEFYGGKLK------------TWSD 2744

  Fly   535 LTNP----------QFPIIFQATHG------VTNREQNSTSSYNNLEAEVICWYVKRLINDRVVG 583
            |..|          ..|:||.:..|      |:..|.|..|..|..|...:...:|:|..||.|.
  Rat  2745 LKRPPSLLGHVGKQSCPVIFGSVQGYEQKLLVSTEEGNENSRANPEEVTEVVRIIKQLTLDRTVD 2809

  Fly   584 QEDVGIVAPYTAQGKLVTKLLQSKGYPNVEVGSVETYQGREKTIIIASLVKSFTN---------- 638
            .:||.::.||.||...:::.|..:|...|.|.|:...||.|...:|.|.|::...
  Rat  2810 PKDVAVLTPYNAQAAAISRGLMQRGVTGVTVTSITKSQGSEWRYVIVSTVRTCPRSDMDQRPTKS 2874

  Fly   639 -----MGFMCNPRRVNVLLSRAKALLILVGNPVTLRHHSDFKFVINECKKHGTYLLKKRDSGQRP 698
                 :||:.:|.:|||.::||:..|.::|:.:.||....:..::..|:...:.:..:|...||.
  Rat  2875 WLKKFLGFVVDPHQVNVAITRAQEGLCIIGDHLLLRCCPLWHRLLGFCEAQNSLVPAERVRVQRK 2939

  Fly   699 HIL 701
            ..|
  Rat  2940 SAL 2942

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mov10	NP_611185.3	DEXXQc_Helz-like	251..499	CDD:350796	71/265 (27%)
		DNA2	<388..684	CDD:440729	97/326 (30%)
Helz2	NP_001292205.1	DEAD-like_helicase_N	759..989	CDD:475120
		AAA_12	974..1160	CDD:463780
		RNB	1565..1923	CDD:214935
		DEXXc_HELZ2-C	2446..2721	CDD:350798	76/288 (26%)
		AAA_12	2701..2906	CDD:463780	63/231 (27%)