Protein Alignment CG8950 and LOC1272621

DIOPT Version :10

• Sequence 1: NP_611184.1
• Gene: CG8950 / 36921
• FlyBaseID: FBgn0034186
• Length: 868
• Species: Drosophila melanogaster
• Sequence 2: XP_311521.4
• Gene: LOC1272621 / 1272621
• VectorBaseID: AGAMI1_009391
• Length: 872
• Species: Anopheles gambiae
• Alignment Length: 912
• Identity: 315/912 - (34%)
• Similarity: 495/912 - (54%)
• Gaps: 84/912 - (9%)

  Fly     1 MADS----DSNEVLIEEIDSNDVPENELEQFQETE--PLRV---------VDIIDCDTDGERRCI 50
            ||||    |::.|.|||::.::|.|::|.:|.|.:  |..:         ......::..:....
Mosquito     1 MADSDVEYDASNVEIEELEVDEVDESDLSEFVEVQQHPAMMQTGSYNAPSTSSAGGNSSAQSESE 65

  Fly    51 ADDE---EEGALIKRYVQGVQCLEFPDFCTKLEASDEDEEGNDEEPSEAAGSIEKPNTSAQAKTS 112
            .|||   :...|||:.|  .:.:.|.::..:::..|:    .|:|.:|...|.:|..|..|..::
Mosquito    66 TDDENTHQREVLIKKLV--AREITFSEYQARMQQDDD----LDDEDAEVDQSHKKKTTFFQDYSN 124

  Fly   113 QEQST------GSGRSGGGGFRKSQ---LSTALQGLMGEANLSFVYGRYETAERICMEIIRQNPL 168
            ..:..      ||.|:.|....:.|   |..|||||||:|||.:..|...|||.:|||||||.||
Mosquito   125 ARRDVLRGNLQGSPRTEGKVTLRRQRRFLPAALQGLMGQANLCYARGDVRTAEDLCMEIIRQVPL 189

  Fly   169 ASEPFYTLAEIYENRDEVKFLNFSTLAAHLNPQDRDMWIRVSDLLVQQGNLARARLIYTKAIKML 233
            |.|||.|||:|:|..|..|:|.:|.:||||||.|.:.|.||:::.:::|::..|...||::|:..
Mosquito   190 AHEPFITLAQIHEMDDPEKYLQYSQIAAHLNPSDAEQWARVAEIFIERGDIDEALKCYTRSIRAN 254

  Fly   234 PKVYQLRLRKAQLLQKMGETNASMFTYLKMLPLMPPDEWKMCLNTAKNVARYFHVLEKHSLALEA 298
            ||...:||::|:|::...|..|..: |..|||.:|.::....::.||.||..||.....|.||:|
Mosquito   255 PKNIDMRLKRARLMETRDEKQAFKY-YYNMLPYIPKEQADFLISIAKRVAEKFHKETNVSAALDA 318

  Fly   299 MEGAYSVCGARFTLEDINIYLELLILNKQYAKVLRCLRERTNFELEN---DQEESLELI--YFCE 358
            |:.||.....:|.:||||:.:||||.|..|.:.|..|....|.||.|   ...|..:|.  :..:
Mosquito   319 MQQAYRTAKEKFNMEDINLLVELLIANGHYRRALDILAVHANVELHNYDMGAAEGTQLSPNFSID 383

  Fly   359 IPDDYVPELRAKLCVSLIHMRAHHLLGYLIQNVQEHITLTADRVELYMDITEALMQEHKYAEAIA 423
            ||||.|.:||.||.|.|:|::........|.::..||. ..:..:.|:|:.||||.|..|.:|:.
Mosquito   384 IPDDIVLDLRTKLAVVLVHLKCEQCFDKAIDDILTHID-PENAGDCYLDVAEALMNEEHYHQALR 447

  Fly   424 LMSPITDGDTVECPAFVWLRQAECLRQLNRTNEAIQSYEKVVQLAPFCYDARFTLSALLKQQGRH 488
            |:.|:.........| ||||.|:|.|.:...:|||..||||:.||.. .|||..|:||||:||::
Mosquito   448 LLVPLIKSKKFSLAA-VWLRYADCSRCIENYDEAIVGYEKVISLAHH-LDARLALAALLKKQGKY 510

  Fly   489 EEAVQALEQPGEAEGQPLIARLLYERCVMLQQIGRIEEFLDVGYALLSRHSIKLYNREEMMAAAN 553
            :||:|||||  :.:.:.|...:|:|||::|.::||.::||..|:.||:||..::..|:::...::
Mosquito   511 DEALQALEQ--DPDKEYLDPEVLHERCLLLHEVGRYQQFLAAGFMLLARHCYQIRKRQDIAVLSH 573

  Fly   554 GGSAYNSESLKTIIQMRSKAVDNSAEQDLQDPAKNAASETSDLTVKDEFELFRELVRTAFKHGMH 618
              ..|:            :..|.:..:.:.|....     :||:|:.|:||...|:..|.:...:
Mosquito   574 --VKYH------------ECKDRTPGEGVPDFVTG-----NDLSVETEWELVLRLLTVADELRDY 619

  Fly   619 SAAEKICFAMVTTKRFTYYHHEIERIMVLTCYYNDDCAIAFSYLRELI-----------AKQPSQ 672
            :...|:.|.:.|:|||..|..|::::.:..|.||.|.....:.:|:.|           |.:.:.
Mosquito   620 TYYMKLVFTLQTSKRFYNYRPELQQLALTACIYNRDPTFGLNIIRDQIRPLFNLKGDAFAAKINH 684

  Fly   673 TTLWNMLSLMIQKGDEVRYYRYMRRLMQRH-PVDTKPMRIFQGHYHLNCASFKYALNIYMPILRE 736
            ..|||:.:|:|....:|||:||:.|:..|. .:...| ::...:|||||:::|||||.|..|...
Mosquito   685 PQLWNLFNLVIFISGDVRYHRYLARVFFRSVGIGVYP-KVLIANYHLNCSTYKYALNEYNKIYLV 748

  Fly   737 NPDPLVALCIAVAFNQLSLQKKVLRKSASVAQAVAFGQRYKELRSAGHELADCAAQQEIFYNIGR 801
            ..|||.|:.|||...|::.||...:|.:.:|||..|.::|  |.....||     :.|.|||:||
Mosquito   749 TNDPLHAMMIAVTLTQIACQKFTNKKQSLIAQANVFMEKY--LTGRPEEL-----RHEAFYNLGR 806

  Fly   802 IYHQANILHLAVDYYEKALAVPVHPLIAEHESTLGLQHEVAFNLHLIYRANGNKWKARQYLMRYC 866
            :|||..:||||||||::.|:.. ..::.|:...|.|:.|.||||..||:.:||...||:||..|.
Mosquito   807 MYHQLGLLHLAVDYYKRVLSFD-SAVVKENPQYLDLKAEAAFNLSFIYKRSGNYELARKYLYEYI 870

  Fly   867 VV 868
            .|
Mosquito   871 QV 872

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8950	NP_611184.1	BepA	133..268	CDD:443813	63/134 (47%)
		TPR repeat	139..164	CDD:276809	14/24 (58%)
		TPR repeat	169..198	CDD:276809	15/28 (54%)
		TPR repeat	203..231	CDD:276809	7/27 (26%)
		TPR repeat	237..264	CDD:276809	7/26 (27%)
		Spy	318..>515	CDD:443119	77/201 (38%)
		TPR repeat	402..430	CDD:276809	11/27 (41%)
		TPR repeat	435..467	CDD:276809	15/31 (48%)
		LapB	438..702	CDD:442196	87/274 (32%)
		TPR repeat	472..497	CDD:276809	15/24 (63%)
LOC1272621	XP_311521.4	None