Protein Alignment fat-spondin and spon2a

DIOPT Version :10

• Sequence 1: NP_477435.1
• Gene: fat-spondin / 36919
• FlyBaseID: FBgn0026721
• Length: 763
• Species: Drosophila melanogaster
• Sequence 2: NP_571082.1
• Gene: spon2a / 30201
• ZFINID: ZDB-GENE-990415-160
• Length: 334
• Species: Danio rerio
• Alignment Length: 297
• Identity: 98/297 - (32%)
• Similarity: 151/297 - (50%)
• Gaps: 15/297 - (5%)

  Fly   184 ECCACDEAKYSFVFEGIWSNETHPKDYPFAIWLTHFSDVIGASHESNFSFWGENHIATAGFRSLA 248
            ||.|...|.|..||.|.||.:|.||.||.......:|.::..:|...:..|.|...|:.|.:|.|
Zfish    37 ECSARGPASYIVVFTGHWSPQTFPKQYPLFRPPAQWSKLMVVTHNEQYRLWQEGAPASDGMKSFA 101

  Fly   249 EWGSPAALETELRANGPKLR------TLIKAAGLWYPNVNQNTSSKFRVDRKHPKVSLVSMFGPS 307
            |.|    |..:|..:..:.|      ::.:.||:  |:...::|::..:..:.|.|||:....||
Zfish   102 EQG----LTVDLVKDAKEARKRRSVGSMYRTAGI--PSGIGHSSTEVLLTPRSPLVSLIVKLIPS 160

  Fly   308 PDWVVGISGLDLCTEDCSWKESMDFDLFPWDAGTDSGISYMSPNSETQPPERMYRITTMYPEDPR 372
            |||.||:.||:|| |...||:.:.|||.|:|||||||.::.|||..|.|||.:..||:..|..|.
Zfish   161 PDWFVGVDGLNLC-EGGKWKQEVTFDLHPFDAGTDSGFTFSSPNFPTTPPENITMITSQKPNHPA 224

  Fly   373 APFYNPKSREMTPLAKLYLRREKIVSRNCDDEFLQALQLEVSDDAEEQDTRAECRVGDYSAWSPC 437
            ..||.|:..|:.|||.::::|:..:.....:.....:..:.|......:|..:|.|..:|:|..|
Zfish   225 NSFYYPRLNELPPLATIWVKRQSRLPVRQQNRLSNHILPDASKPHRFSETPLDCEVSMWSSWGLC 289

  Fly   438 SVSCGK-GIRMRSRQYLYPAAADQNKCARQLVAKEMC 473
            ...|.: |:|.|:|..|...|...:.|. :|..:|.|
Zfish   290 FGPCARGGLRHRTRYILLKPANSGSPCP-ELEEQEEC 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fat-spondin	NP_477435.1	Reeler	24..172	CDD:260081
		Spond_N	191..385	CDD:461924	73/199 (37%)
		PTZ00441	<419..>497	CDD:240420	17/56 (30%)
		TSP1_spondin	426..>463	CDD:480609	12/37 (32%)
		TSP1_spondin	515..566	CDD:480609
		TSP1_spondin	578..630	CDD:480609
		Kunitz-type	644..695	CDD:444694
		TSP1_spondin	711..763	CDD:465948
spon2a	NP_571082.1	Spond_N	44..237	CDD:461924	73/199 (37%)
		TSP1_spondin	278..330	CDD:465948	16/49 (33%)