DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SmydA-6 and SET5

DIOPT Version :9

Sequence 1:	NP_611182.1	Gene:	SmydA-6 / 36917	FlyBaseID:	FBgn0034183	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_012077.1	Gene:	SET5 / 856614	SGDID:	S000001250	Length:	526	Species:	Saccharomyces cerevisiae

Alignment Length:	358	Identity:	77/358 - (21%)
Similarity:	129/358 - (36%)	Gaps:	116/358 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 DFARKCEIK-QNDTLGRFAVALCNVRAGETLLLEN-PIVVLP-------LMGERRCSKC----FN 58
            |...|.|:| .:|..||...|..:...|:.:|.|| |||.:|       :...:.|::|    ::
Yeast   109 DSDAKVEVKFIDDEHGRGLFAKRDFSKGQIILKENKPIVYIPPLDKLFLISNGKACARCGKALYD 173

  Fly    59 LTES-------FCRKCRLLALCEDC-----SDHD--------------------------ERDC- 84
            ||:.       .|..|:.:...|.|     |.|:                          |:.|
Yeast   174 LTQHKIMVHYLDCEVCKAIWCSEKCKKAHASLHELLYHSWRSNRIDILHAGNWKRFVNYCEKYCF 238

  Fly    85 -------------------------KRLAEMNFSDDQVELLQKKEHTEIQPVLKCLLLREHEETL 124
                                     ::||.::    |.|.::.::.:.|......|    :..|:
Yeast   239 TAAFSVGLIYGSMLLDTTGEVKEQWQKLASIS----QRERIKLRDASGIGSTFSLL----NGTTV 295

  Fly   125 PLYEEMSQMDSQLMTRRGTE-------VWKNYQEHAFTPLDYGGVLAQLRGAADEDLVQGLLGIL 182
            ...||     |...|::|.|       ||:...|.      :.|...:.....|.:....::|..
Yeast   296 HTEEE-----SDNGTKKGVEKNIDDETVWEKCYEL------FCGAFPKASEEIDFEKFLTMIGTF 349

  Fly   183 DINAYEIRAPEVGGAMRGLYRRAGLFAHSCTPNLVI-SIDDEQRIKVYANRFIAAGEILYNCYTN 246
            :||.|..:          :|.......|.|.||..| .:::.:.::::|.:.|..||.:...|.|
Yeast   350 NINQYNGQ----------VYHWISFINHDCEPNAYIEQVEEHEELRLHARKPIKKGEQIRITYVN 404

  Fly   247 VLLGTEERRKILKVGKCFDCSCPRCQDPTELGT 279
            .|.|...||:.|:|...|.|.|.|||:  ||.|
Yeast   405 PLHGVRLRRRELRVNWGFLCQCDRCQN--ELST 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-6	NP_611182.1	SET	<179..244	CDD:279228	14/65 (22%)
SET5	NP_012077.1	SET	41..526	CDD:225491	77/358 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4564
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.760