Protein Alignment SmydA-6 and ZMYND15

DIOPT Version :10

• Sequence 1: NP_611182.1
• Gene: SmydA-6 / 36917
• FlyBaseID: FBgn0034183
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: XP_047292879.1
• Gene: ZMYND15 / 84225
• HGNCID: 20997
• Length: 810
• Species: Homo sapiens
• Alignment Length: 363
• Identity: 77/363 - (21%)
• Similarity: 116/363 - (31%)
• Gaps: 146/363 - (40%)

  Fly    67 CRLLALCEDCSDHDERDCKRLAEMNFSDDQVELLQKKEHTEIQPV-LKCLLL--REHEETLPLYE 128
            ||     ||..:::.|..||               |.:.:|..|: :.||||  .||...|.:
Human   246 CR-----EDRVENETRPQKR---------------KGQRSEAAPLHVSCLLLVTDEHGTILGI-- 288

  Fly   129 EMSQMDSQLMTRRGTEVWKNYQEHAFTPLDYGGVLAQLRGAADEDLVQGLLGIL------DINAY 187
                 |..:...:||..|                     |:..:||......:|      .:.:.
Human   289 -----DLLVDGAQGTASW---------------------GSGTKDLAPWAYALLCHSMACPMGSG 327

  Fly   188 EIRAPE---VGGAMRGLYRRAGLFAHSCTPNLVISIDDEQRIKVYANR--FIAAGEILYNCYTNV 247
            :.|.|.   ||.|.  |:|.    ..|..|.|.:.: .:..::.:..|  |..|.
Human   328 DPRKPRQLTVGDAR--LHRE----LESLVPRLGVKL-AKTPMRTWGPRPGFTFAS---------- 375

  Fly   248 LLGTEERRKILKVGKCFDCSCPRCQDPTELGTHMSSF-----ICSQCSCV--DGYIVRQPDTGIW 305
                      |:...|..|             |..||     .|.|||.|  .|....:.|   |
Human   376 ----------LRARTCHVC-------------HRHSFEAKLTPCPQCSAVLYCGEACLRAD---W 414

  Fly   306 Q-CLLNPEHTLKQEFVSNMLERAKE----------EIFHARDDIYRQELLLAKLSRLLHRNHFLM 359
            | |..:..|......::..:|||.|          |:   ..:.:.:|..||  ||.|.|.::..
Human   415 QRCPDDVSHRFWCPRLAAFMERAGELATLPFTYTAEV---TSETFNKEAFLA--SRGLTRGYWTQ 474

  Fly   360 LDL-----------KQNI--ASILR-----QILQNMGT 379
            |.:           :.|.  .|:||     |:||..||
Human   475 LSMLIPGPGFSRHPRGNTPSLSLLRGGDPYQLLQGDGT 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-6	NP_611182.1	SET_SMYD	<185..271	CDD:380997	16/90 (18%)
ZMYND15	XP_047292879.1	zf-MYND	381..427	CDD:460312	16/61 (26%)
		MSS51_C	552..746	CDD:466330