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Protein Alignment SmydA-6 and SMYD3

DIOPT Version :9

Sequence 1:	NP_611182.1	Gene:	SmydA-6 / 36917	FlyBaseID:	FBgn0034183	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_001161212.1	Gene:	SMYD3 / 64754	HGNCID:	15513	Length:	428	Species:	Homo sapiens

Alignment Length:	484	Identity:	105/484 - (21%)
Similarity:	175/484 - (36%)	Gaps:	130/484 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 ALCNVRAGETLLLENPIVVLPLMGERR--CSKCFNLTESF--CRKCRLLALCE-DCS-----DHD 80
            |:..:|.||.|...:|:......|.|.  |.:|....|..  |.:||:...|. .|.     ||
Human    20 AVTPLRPGELLFRSDPLAYTVCKGSRGVVCDRCLLGKEKLMRCSQCRVAKYCSAKCQKKAWPDH- 83

  Fly    81 ERDCKRL--AEMNFSDDQVELLQKKEHTEIQPVLKCL--LLREHEETLPLYEEMSQM-----DSQ 136
            :|:||.|  .:..:..|.|.||.:       .|.|.:  ...|.|:....|:..|.:     |.:
Human    84 KRECKCLKSCKPRYPPDSVRLLGR-------VVFKLMDGAPSESEKLYSFYDLESNINKLTEDKK 141

  Fly   137 LMTRRGTEVWKNYQEHAFTPLDYGGVLAQLRGAADEDLVQGLLGILDINAYEIRAPEVGGAMRGL 201
            ...|:....::::.......      .:||..|.  ||.:....:: .|::.|...|:.....||
Human   142 EGLRQLVMTFQHFMREEIQD------ASQLPPAF--DLFEAFAKVI-CNSFTICNAEMQEVGVGL 197

  Fly   202 YRRAGLFAHSCTPNLVISIDDEQRIKVYANRFIAAGEILYNCYTNVLLGTEERRKILKVGKCFDC 266
            |....|..|||.||..| :.:...:.:.|.|.|..||.|..||.::|:.:|||||.|:...||:|
Human   198 YPSISLLNHSCDPNCSI-VFNGPHLLLRAVRDIEVGEELTICYLDMLMTSEERRKQLRDQYCFEC 261

  Fly   267 SCPRCQDPTELGTHMSSFICSQCSCVDGYIVRQPDTGIWQCLLNPEHTLKQEFVSNMLERAKEEI 331
            .|.|||...:....::.                 |..:|            :.|...|::.:|..
Human   262 DCFRCQTQDKDADMLTG-----------------DEQVW------------KEVQESLKKIEELK 297

  Fly   332 FHARDDIYRQELLLAKLSRLLHRNHFLMLDLKQNIASILRQILQNMGTRPNKKVYERKIRLC--- 393
            .|     ::.|.:||....:                     |..|....|:..:|:.|:..|
Human   298 AH-----WKWEQVLAMCQAI---------------------ISSNSERLPDINIYQLKVLDCAMD 336

  Fly   394 --------QEILLV-------LKVVTPGISRLKAIALYELANTQAELARKMYTE----------- 432
                    :|.|..       .::..||...::.:.:.::...|  |.:.|:.:
Human   337 ACINLGLLEEALFYGTRTMEPYRIFFPGSHPVRGVQVMKVGKLQ--LHQGMFPQAMKNLRLAFDI 399

  Fly   433 ------MEHS-ANDLLAELERVEVMLRES 454
                  .||| ..||:..||..:..:|.|
Human   400 MRVTHGREHSLIEDLILLLEECDANIRAS 428

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.