Protein Alignment SmydA-6 and Smyd4

DIOPT Version :9

• Sequence 1: NP_611182.1
• Gene: SmydA-6 / 36917
• FlyBaseID: FBgn0034183
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_001099280.1
• Gene: Smyd4 / 287525
• RGDID: 1307369
• Length: 801
• Species: Rattus norvegicus
• Alignment Length: 636
• Identity: 132/636 - (20%)
• Similarity: 223/636 - (35%)
• Gaps: 208/636 - (32%)

  Fly     2 AAVT---DDFARKCEIKQ-----------NDTL-GRFAVALCNVRAGETLLLENPIVVLPLMGE- 50
            ||:|   :|.|...|.||           .|.| ||..||..::..||.|:.|:..|.:...||
  Rat   210 AALTKALEDMALGEENKQISGASLSVSLCTDPLKGRHLVATKDILPGELLVKEDAFVSVLNPGEM 274

  Fly    51 ---RRC-----SKCFNLTESFCRKCRLLAL----CEDCS--DHDERDCKRLAEMNFSDDQ----- 96
               |.|     .......:.:|.:|....|    |..||  .:..::|.:.|..::...:
  Rat   275 PPLRHCLENKWDTRVTSADLYCHRCLRHTLATVPCGGCSYAKYCSQECVQQAWDHYHSTECSLGG 339

  Fly    97 --------------VELLQKKEHTEIQPVLK-----------CL-----LLR-----------EH 120
                          :.||.:.|  ::..|::           ||     |::           |:
  Rat   340 LLLTLGVFCHVALRMTLLARFE--DVDRVIRMICDKTGRKDTCLPESKDLVKTFGYTNQGESEEN 402

  Fly   121 EET----LP------LYEEMSQMDSQLMTRRGTEVWKNYQEHAF-TPLDYGGVLAQLRGAADEDL 174
            .||    :|      .||  :..|:.|.....||  |:..||.| ..:....:..||:..:.:..
  Rat   403 SETCEPSIPGCNVNGKYE--NNYDAVLSLLPHTE--KHSPEHKFICAVSVSALCRQLKATSLQAQ 463

  Fly   175 VQGL------------------LGI--------LDINAYEIRAPEVGGAMR-------------G 200
            ..||                  .|:        |..||..|.:....|:..             |
  Rat   464 TTGLKSPRLKAVTPGLCTDLTVWGVAMLQHMLQLQCNAQAITSICYAGSKESIITNSRQVRLATG 528

  Fly   201 LYRRAGLFAHSCTPNLVISIDDEQRIKVYANRFIAAGEILYNCY--TNVLLGTEERRKILKVGKC 263
            ::....|..|||:||..:|..... ..:.|.:.||.|:.:.:||  ....:|..||::.|.....
  Rat   529 VFPVVSLLNHSCSPNTSVSFTSTV-ATIRAAQQIAKGQEILHCYGPHESRMGVAERQQRLSSQYF 592

  Fly   264 FDCSCPRCQDPT---ELGTHMSSFICSQCSCVDGYIVRQPDTGIWQCLLNPEHTLKQEFVSNMLE 325
            ||||||.|...|   .:.....:|.|:.|        |.|..|      |...:...|..:|.:.
  Rat   593 FDCSCPACHAETLRAAVAPRWEAFCCNTC--------RVPMQG------NDVLSCSNESCTNSVS 643

  Fly   326 RAKEEIFHARDDIYRQELLLAKLSRLLHRNHFLMLDLKQNIASILRQILQNMGTRPNKKVYERKI 390
            |                      .||:.|    :.||:|.:.: .:::|::  .||.:.:  :::
  Rat   644 R----------------------DRLVSR----LQDLQQQVHT-AQKLLRS--DRPEQAI--QQL 677

  Fly   391 RLCQEIL--------LVLKVVTPGISRLKAIALYELANTQAELARKM-YTEMEH--SANDLLAEL 444
            ..||...        .||..:..|:::..| .|.:...:.|.:.:.: ..|..|  |:.::..||
  Rat   678 LECQRAAENFLSAEHTVLGEIEDGLAQAYA-TLGDWRQSAAHVQKSLQVVEARHGPSSVEIGHEL 741

  Fly   445 ERVEVMLRESLRMLLFEPLATPEG-----QLTRSMLRELKELQDDIKNLRE 490
            .:        |..:||..||.||.     :..:.:|.......|:::.|||
  Rat   742 FK--------LAQVLFNGLAVPEALDAIWKAEKILLVHCGPESDEVQELRE 784

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-6	NP_611182.1	SET	<179..244	CDD:279228	18/85 (21%)
Smyd4	NP_001099280.1	TPR_11	68..132	CDD:290150
		TPR repeat	68..96	CDD:276809
		TPR repeat	101..136	CDD:276809
		zf-MYND	296..335	CDD:280009	8/38 (21%)
		SET	<526..572	CDD:279228	13/46 (28%)
		TPR_12	692..>748	CDD:290160	12/64 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810