Protein Alignment SmydA-6 and set-30

DIOPT Version :10

• Sequence 1: NP_611182.1
• Gene: SmydA-6 / 36917
• FlyBaseID: FBgn0034183
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_508850.2
• Gene: set-30 / 180772
• WormBaseID: WBGene00022499
• Length: 560
• Species: Caenorhabditis elegans
• Alignment Length: 545
• Identity: 116/545 - (21%)
• Similarity: 189/545 - (34%)
• Gaps: 163/545 - (29%)

  Fly    53 CSKCFNLTESFCRKCRLLALCEDCSDHDERDCKRLAEMNFSDDQVELLQKKEHT-EIQPVLKCLL 116
            |:|     :.:|..|        ..::.|..|::.....|...|.|.....:|. |..|:.||..
 Worm    35 CTK-----DDYCWTC--------LGENVELTCEQCKVAKFCSKQCETSGAIDHKYECGPLKKCPD 86

  Fly   117 LREHEETL----PLYEEM-SQMDSQL--------MTRRGTEVWKN-----YQEHAFTPL--DYGG 161
            |...|..|    ..|::: |..|..:        ..|...|:|::     ..|:|....  .|..
 Worm    87 LNTDERMLIRIVGRYKDIHSGKDKSIDGFYNNRESKRSVMEIWEHCADMKKDENAMKSFKKTYDR 151

  Fly   162 V--LAQLRGAADEDLVQGLLGILDINAYEIR----APEVGGAMRGLYRRAGLFAHSCTPNLVISI 220
            |  ........||::...|.....||.:.|.    ..|:|   :|||.....:.|||.||.:.|
 Worm   152 VKQFGDTNHLMDEEVTFQLHSRNFINRHSISNVDYLREIG---KGLYLDLCKYDHSCRPNAIYS- 212

  Fly   221 DDEQRIKVYANRFIAAGEILYNCYTNVLLGTEE---------------RRKILKVGKCFDCSCPR 270
                     .|..:|....|::   ||.|...|               ||.:||....|:|.|.|
 Worm   213 ---------CNGIVAKLRALHD---NVDLENVETTHYTYIELPPCKIQRRHMLKETWYFECHCER 265

  Fly   271 CQDPTELGTHMSSFICSQCSCVDGY----IVRQPDTGIWQCLLNPE----------HTLKQEF-- 319
            |.||.:  ..::|.:|..|.....|    .:..|     :...|||          .||.:|:
 Worm   266 CDDPDD--NWLTSVLCPVCISKTEYRKTIKLHGP-----EAYANPETLEIVCDRCSTTLDREYIF 323

  Fly   320 --------VSNMLERAKEEIFHARDDIYRQELL------LAKLSRLLHRNHFLMLDLKQNIASIL 370
                    :...:|.|::|   .:|.|   |||      |....|:|..::.....|   ||:::
 Worm   324 MALDGMRTIRRTVEGAEDE---TKDPI---ELLKIYQGALMTYERILPMSNAYFCQL---IAAMI 379

  Fly   371 RQILQNMGTRPNKKVYERKIRL-CQE-ILLVLKVVTPGISRLKAIALYELANTQAELA------- 426
            ..|.:...|:..:.|....:.| |:. :..|.:...|.    ||:...::.....|||
 Worm   380 PLISRVSMTKKERLVASLDLHLKCETFVRYVYRHAHPS----KAMHFLQMGQLHLELANDKDAAR 440

  Fly   427 --------------------RKMYTEMEHSANDLLAELER--VEVMLR-ESLRMLLFEPLATPEG 468
                                ::....|:|:.:.|: :.:|  |.|:.| ...:..|.|...|.:
 Worm   441 CLIEAHRIMDYLFGADHFLSKQTKGFMDHALSSLM-QFQRNFVNVLDRVPEAKQALEERFMTAD- 503

  Fly   469 QLTRSMLRELKELQDDIKNLRESDD 493
                    |.|.|:|..||.|:.::
 Worm   504 --------EKKALKDSEKNKRKRNN 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-6	NP_611182.1	SET_SMYD	<185..271	CDD:380997	27/104 (26%)
set-30	NP_508850.2	zf-MYND	41..78	CDD:460312	8/44 (18%)
		SET_SMYD	<179..266	CDD:380997	26/102 (25%)