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Protein Alignment SmydA-6 and SMYD1

DIOPT Version :9

Sequence 1:	NP_611182.1	Gene:	SmydA-6 / 36917	FlyBaseID:	FBgn0034183	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_938015.1	Gene:	SMYD1 / 150572	HGNCID:	20986	Length:	490	Species:	Homo sapiens

Alignment Length:	462	Identity:	96/462 - (20%)
Similarity:	174/462 - (37%)	Gaps:	120/462 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 CSKCFNLTESF--CRKCRLLALCEDCSDHDERDCKRLAEMNFSDD--QVELLQKKEHTEIQPVLK 113
            |..||...|..  |.:|:....|       :|.|::.|.:|..::  .::...|..:..|:...:
Human    52 CHTCFKRQEKLHRCGQCKFAHYC-------DRTCQKDAWLNHKNECSAIKRYGKVPNENIRLAAR 109

  Fly   114 ---------------CLL----LREHEETLPLYEEMSQMDSQLMTRRGTEVWKNYQEHAFTPLDY 159
                           ||:    |:.|.|.   :.|..|.|.::......:.|.. |...|: :.|
Human   110 IMWRVEREGTGLTEGCLVSVDDLQNHVEH---FGEEEQKDLRVDVDTFLQYWPP-QSQQFS-MQY 169

  Fly   160 GGVLAQLRGAADEDLVQGLLGILDINAYEI---RAPEVGGAMRGLYRRAGLFAHSCTPNLVISID 221
                           :..:.|:::.|.:.:   |..:..|.  |::...||..|.|.||..:..:
Human   170 ---------------ISHIFGVINCNGFTLSDQRGLQAVGV--GIFPNLGLVNHDCWPNCTVIFN 217

  Fly   222 D------------EQRIKVYANRFIAAGEILYNCYTNVLLGTEERRKILKVGKCFDCSCPRCQDP 274
            :            :.||::.|...|:.||.|...|.:.|..:|||::.||....|||:|..||..
Human   218 NGNHEAVKSMFHTQMRIELRALGKISEGEELTVSYIDFLNVSEERKRQLKKQYYFDCTCEHCQKK 282

  Fly   275 TELGTHMSSFICSQCSCVDGYIVRQPDTGIWQCLLNPEHTLKQEFVSNMLERAK---EEIFHARD 336
            .:                |...:...|        ||:.:  ||.|..|::.:|   |:|..||.
Human   283 LK----------------DDLFLGVKD--------NPKPS--QEVVKEMIQFSKDTLEKIDKARS 321

  Fly   337 D-IYRQELLLAKLSR-LLHRNHFLMLDLK---QNIASILRQILQNMGTRPNKKVYERKIRLCQEI 396
            : :|.:   :.||.| .|.:...:..|..   ..:.||:.::|..:........|.|::     :
Human   322 EGLYHE---VVKLCRECLEKQEPVFADTNIYMLRMLSIVSEVLSYLQAFEEASFYARRM-----V 378

  Fly   397 LLVLKVVTPGISRL-KAIALYELANTQA---ELARKMYTE------MEHS-ANDLLAELERVEVM 450
            ...:|:..|..::| .|:....|.|..|   |:...|..:      :.|. ::.:..:||.:.|.
Human   379 DGYMKLYHPNNAQLGMAVMRAGLTNWHAGNIEVGHGMICKAYAILLVTHGPSHPITKDLEAMRVQ 443

  Fly   451 LRESLRM 457
            ....|||
Human   444 TEMELRM 450

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.