DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SmydA-7 and ZMYND15

DIOPT Version :9

Sequence 1:	NP_001261039.1	Gene:	SmydA-7 / 36916	FlyBaseID:	FBgn0034182	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_001254751.1	Gene:	ZMYND15 / 84225	HGNCID:	20997	Length:	750	Species:	Homo sapiens

Alignment Length:	206	Identity:	46/206 - (22%)
Similarity:	65/206 - (31%)	Gaps:	71/206 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   140 EGMWQEHEELVVRPLMESGLADVLPTQELTSDALHAHCIRIDSNSF-------------EVTAKD 191
            :|..::..|...||....|       |...:..||..|:.:.::..             :.||..
Human   176 DGCREDRVENETRPQKRKG-------QRSEAAPLHVSCLLLVTDEHGTILGIDLLVDGAQGTASW 233

  Fly   192 GDTLKGIFVWGATLPHHCVPNTVVALDEQFNMKLYAAVPLQPGDIIYNSYTNPLMGTSQRQHQL- 255
            |...|.:..|...|..|.:                 |.|:..||             .::..||
Human   234 GSGTKDLAPWAYALLCHSM-----------------ACPMGSGD-------------PRKPRQLT 268

  Fly   256 ----RLSRRLECICSRC---LDPTEM-------GTHMSSLKCKECPGFSVCEIDS-NGKLGDWRC 305
                ||.|.||.:..|.   |..|.|       |...:||:.:.|   .||...| ..||..  |
Human   269 VGDARLHRELESLVPRLGVKLAKTPMRTWGPRPGFTFASLRARTC---HVCHRHSFEAKLTP--C 328

  Fly   306 PDCRALLTAAE 316
            |.|.|:|...|
Human   329 PQCSAVLYCGE 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-7	NP_001261039.1	None
ZMYND15	NP_001254751.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	109..199		6/29 (21%)
		zf-MYND	313..359	CDD:280009	12/32 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	565..590
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	709..750
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900