DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SmydA-7 and Smyd4-2

DIOPT Version :9

Sequence 1:	NP_001261039.1	Gene:	SmydA-7 / 36916	FlyBaseID:	FBgn0034182	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_648574.1	Gene:	Smyd4-2 / 39414	FlyBaseID:	FBgn0036282	Length:	663	Species:	Drosophila melanogaster

Alignment Length:	428	Identity:	92/428 - (21%)
Similarity:	141/428 - (32%)	Gaps:	129/428 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 GRHLVASIAIEPGDTILEERPLLVAPHWECHQLKCAQCLQESY---------------VICRRCQ 66
            ||.:||:..:..||.:|.|.|:             |.||:.||               |.|..|.
  Fly   265 GRFVVANEGLRTGDVLLFEEPV-------------AACLEPSYFGTHCHHCFKRLHTPVSCLHCS 316

  Fly    67 VFPLCM------DCNQHDEFECEF--FTSGAGKALCKDILVKNFGIC-----GLLKLLLLLEN-- 116
            ....|.      .|:.:..||||:  ...|:|.::...|.::.|...     ||....||.|:
  Fly   317 GIAFCSAQCMGEACSSYHRFECEYMDLMIGSGMSILCFIALRIFTQAPSLEQGLATANLLFEHLC 381

  Fly   117 ----PRTKGD-------CQMLIDVPINLSDY---RDGEGMWQEHEELVVRPLMESGLADVLPTQE 167
                .|...|       ...|:.: :..|.|   |..||:.....||.|...: .||..||
  Fly   382 SHEEDRQPDDYLRRALMSGFLLRI-LQKSLYFGRRKTEGVNPTAVELQVATAL-LGLLQVL---- 440

  Fly   168 LTSDALHAHCI---------RIDSNSFEVTAKDGDTLKGIFVWGATLPHHCVPNTVVALDEQFNM 223
                ..:||.|         |.|.:.....|      .|::..|:...|.|.|:|......: .:
  Fly   441 ----QYNAHQIYQTQVTEEHRFDGSKTVYLA------AGLYGTGSYFNHECWPSTACHFVGK-KL 494

  Fly   224 KLYAAVPLQPGDIIYNSYTNPLM---GTSQRQHQLRLSRRLECICSRC---------LDPTEMGT 276
            .|.|..|.:..:::..:| .|:.   ...:||..||......|.|..|         || .::..
  Fly   495 VLTATRPHRANELVAVNY-GPIFIKNNLKERQRSLRGRYSFSCSCMACQENWPLLQKLD-KQVRF 557

  Fly   277 HMSSLKCKECPGFSVCEIDSNGKLGDWRCPDCRALLTAAE-------VHELQAAVGSALVDAMGD 334
            ..:|..|.....|      ......|.|||.||..::..|       :.||......|: :|...
  Fly   558 WCTSANCSNLLKF------PKDLAKDVRCPRCRKNISLKESVAKMIKIEELYREAARAM-EAQKT 615

  Fly   335 LQVYEALLTQYGPLLHPNHFMLLDIKQNIASILRAAAL 372
            ::..|.                  .|:::....:.|||
  Fly   616 VEAIEL------------------FKESLDMFFQVAAL 635

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-7	NP_001261039.1	None
Smyd4-2	NP_648574.1	TPR_11	142..205	CDD:290150
		zf-MYND	299..338	CDD:280009	6/38 (16%)
		SET	<474..513	CDD:279228	9/40 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452066
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2084
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740