DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SmydA-7 and smyd1a

DIOPT Version :9

Sequence 1:	NP_001261039.1	Gene:	SmydA-7 / 36916	FlyBaseID:	FBgn0034182	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_991103.2	Gene:	smyd1a / 321245	ZFINID:	ZDB-GENE-030131-9825	Length:	485	Species:	Danio rerio

Alignment Length:	456	Identity:	98/456 - (21%)
Similarity:	152/456 - (33%)	Gaps:	167/456 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 NPRTKGDCQMLIDVPINLSDYRDGEGMWQEHEE-----------------LVVRPL----MESGL 159
            ||.....|:.     .:..|.......|.||.:                 ||.|.|    ..:||
Zfish    61 NPHRCAQCKF-----AHYCDRTCQRAAWDEHRKECSAIRNIGKAPNENVRLVARILWRIQKHTGL 120

  Fly   160 ADVLPTQELTSDALHAHC----------IRID--------------------SNSFEVTAKDGDT 194
              |..:|..|.|.|..|.          :::|                    |:.|.|.:.:|.|
Zfish   121 --VSDSQLTTLDMLEDHLSRMTPEDLKELKVDVKTFYTYWPKKSKAVGEDYVSHLFGVISCNGFT 183

  Fly   195 LK----------GIFVWGATLPHHCVPNTVV--------ALDEQFN----MKLYAAVPLQPGDII 237
            |.          |:|.....:.|.|.||..|        |||..|:    ::|.|..|:..|..:
Zfish   184 LSDQRGLQSVGIGLFPNLCLVNHDCWPNCTVILNHGDQSALDASFHSSRRIELRALEPISAGQEL 248

  Fly   238 YNSYTNPLMGTSQRQHQLRLSRRLECICSRCLD-----------PTEMGTHMSSLKCKECPGFS- 290
            ..||.:.|..::.||..|:.....:|.|..|::           |||.|...|:...|:...||
Zfish   249 TVSYVDFLSVSTDRQRLLQQQYYFDCKCEHCVNGTKDELMTAVKPTEDGKQPSAEVVKQLTDFSL 313

  Fly   291 --VCEIDSNGKLGDWR-----CPDC----------------RALLTAAEV----HELQAAVGSAL 328
              :.:|::....|::.     |.:|                |.|.||:||    .:.|.|.|.|
Zfish   314 QALVKIEAARAQGNFHEVIRICRECLEKQDPVFADTNVHVLRVLSTASEVLSFLQQFQEAAGYA- 377

  Fly   329 VDAMGDLQVYEALLTQYGPLLHPNHFMLLDIKQNIASILRAAALMNSMDQPCKKLLARRVELCSD 393
                      :.::..|..|.|||:..|      ..:|:||..         ....|..:|....
Zfish   378 ----------QRMVDGYMKLYHPNNAQL------GMAIMRAGV---------THWHAGLIEAAHG 417

  Fly   394 LLPVCRAVVPGISKLYAIGLFEY---------LLALVELVELQFAESDLSKKEYVAH-LRTASLV 448
            |  :|||        |.|.:..:         |.|:....|::...  ..:.|:|.| :|.|:|.
Zfish   418 L--ICRA--------YGILMITHGPHHPISKDLEAMRRQTEMELRM--FKQNEHVYHSMREAALT 470

  Fly   449 A 449
            :
Zfish   471 S 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-7	NP_001261039.1	None
smyd1a	NP_991103.2	zf-MYND	52..90	CDD:280009	7/33 (21%)
smyd1a	NP_991103.2	SET	<203..252	CDD:279228	13/48 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D981799at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820