Protein Alignment SmydA-7 and Smyd2

DIOPT Version :10

• Sequence 1: NP_611181.1
• Gene: SmydA-7 / 36916
• FlyBaseID: FBgn0034182
• Length: 488
• Species: Drosophila melanogaster
• Sequence 2: NP_996733.1
• Gene: Smyd2 / 289372
• RGDID: 727785
• Length: 433
• Species: Rattus norvegicus
• Alignment Length: 448
• Identity: 88/448 - (19%)
• Similarity: 146/448 - (32%)
• Gaps: 134/448 - (29%)

  Fly    17 GRHLVASIAIEPGDTILEERPLLVAPHWEC--------HQLKCAQCLQESYVICRRC-QVFPLCM 72
            ||.|.|......||.      |...|.:.|        |..:|....:|....|.|| |.|...:
  Rat    18 GRGLRALRPFHVGDL------LFSCPAYACVLTVGERGHHCECCFARKEGLSKCGRCKQAFYCDV 76

  Fly    73 DCNQHD----EFEC-------EFFTSGAGKALCKDILVKNFGICGLLKLLLLLENPRTKGDCQML 126
            :|.:.|    :.||       |.:.......|...||.|.           .:...||..:..:.
  Rat    77 ECQKEDWPLHKLECSSMVVFGENWNPSETVRLTARILAKQ-----------KMHPERTPSEKLLA 130

  Fly   127 IDVPINLSDYRDGEGMWQEHEELVVRPLMESGLADVLPTQELTSDAL----HAHCI----RIDSN 183
            :....:..|..|.|          .:.|::|   |:....:..|..|    |:..:    :::.|
  Rat   131 VREFESHLDKLDNE----------KKDLIQS---DIAALHQFYSKHLEFPDHSSLVVLFAQVNCN 182

  Fly   184 SFEVTAKDGDTL-KGIFVWGATLPHHCVPNTVVALDEQFNMKLYAAVPLQPGDIIYNSYTNPLMG 247
            .|.:..::...| ..||...|.:.|.|.||.:|...... .::.|...:.|||.::.||.:.|..
  Rat   183 GFTIEDEELSHLGSAIFPDVALMNHSCCPNVIVTYKGTL-AEVRAVQEIHPGDEVFTSYIDLLYP 246

  Fly   248 TSQRQHQLRLSRRLECICSRCLDPTEMGTHMSSLKCKECPG------------------------ 288
            |..|..:||.|....|.|..|....:....:...|....|.
  Rat   247 TEDRNDRLRDSYFFTCECRECTTKDKDKAKVEIRKLSNPPQAEAIRDMVRYARNVIEEFRRAKHY 311

  Fly   289 ------FSVCEI----------DSNGKLGDWRCPDCRALLTAAEVHELQAAVGSALVDAMGDLQV 337
                  ..:||:          |||..:                :|.:..|:|..|.     :|.
  Rat   312 KSPSELLEICELSQEKMSSVFEDSNVYM----------------LHMMYQAMGVCLY-----MQD 355

  Fly   338 YEALLTQYGPLL---HPNHFMLLDIKQNIASI-LRAAALMNSM------DQPCKKLLA 385
            :|..| :||..:   :..|:.:..:  |:||: |:...|...:      ::..||.:|
  Rat   356 WEGAL-KYGQKIIKPYSKHYPVYSL--NVASMWLKLGRLYMGLENKAAGEKALKKAIA 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-7	NP_611181.1	SET_SMYD	<178..268	CDD:380997	25/94 (27%)
Smyd2	NP_996733.1	SET_SMYD2	7..269	CDD:380979	63/281 (22%)
		zf-MYND	52..90	CDD:460312	9/37 (24%)
		TPR_10	388..422	CDD:463861	4/23 (17%)