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Protein Alignment SmydA-7 and SMYD1

DIOPT Version :9

Sequence 1:	NP_001261039.1	Gene:	SmydA-7 / 36916	FlyBaseID:	FBgn0034182	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_938015.1	Gene:	SMYD1 / 150572	HGNCID:	20986	Length:	490	Species:	Homo sapiens

Alignment Length:	412	Identity:	90/412 - (21%)
Similarity:	154/412 - (37%)	Gaps:	87/412 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ENIQHAHDEKLGRHLVASIAIEPGDTILEERPL-------LVAPHWECHQL--------KCAQCL 55
            ||::....|..||.|.|:......|.|..||..       ||  ::.||..        :|.||.
Human     7 ENVEVFTAEGKGRGLKATKEFWAADIIFAERAYSAVVFDSLV--NFVCHTCFKRQEKLHRCGQCK 69

  Fly    56 QESYVIC-RRCQVFPLCMDCNQHDEFECEFFTSGAGKALCKDILVKNFGICGLLKLLLLLENP-- 117
            ...|  | |.||     .|...:.:.||        .|:.:...|.|..|....:::..:|..
Human    70 FAHY--CDRTCQ-----KDAWLNHKNEC--------SAIKRYGKVPNENIRLAARIMWRVEREGT 119

  Fly   118 -RTKGDCQMLIDVPINLSDYRDGEGMWQEHEELVVRPLMESGLADVLPTQELTSDALHAHCIR-I 180
             .|:| |.:.:|   :|.::.:..|   |.|:..:|..:::.|....|..:..|....:|... |
Human   120 GLTEG-CLVSVD---DLQNHVEHFG---EEEQKDLRVDVDTFLQYWPPQSQQFSMQYISHIFGVI 177

  Fly   181 DSNSFEVTAKDGDTLKGIFVWG--ATLPHHCVPNTVVALDE------------QFNMKLYAAVPL 231
            :.|.|.::.:.|....|:.::.  ..:.|.|.||..|..:.            |..::|.|...:
Human   178 NCNGFTLSDQRGLQAVGVGIFPNLGLVNHDCWPNCTVIFNNGNHEAVKSMFHTQMRIELRALGKI 242

  Fly   232 QPGDIIYNSYTNPLMGTSQRQHQLRLSRRLECICSRC----LDPTEMGT----HMSSLKCKECPG 288
            ..|:.:..||.:.|..:.:|:.||:.....:|.|..|    .|...:|.    ..|....||...
Human   243 SEGEELTVSYIDFLNVSEERKRQLKKQYYFDCTCEHCQKKLKDDLFLGVKDNPKPSQEVVKEMIQ 307

  Fly   289 FS---VCEIDSNGKLGDWR-----CPDC----RALLTAAEVHELQAAVGSALVDAMGDLQVYE-- 339
            ||   :.:||.....|.:.     |.:|    ..:.....::.|:..  |.:.:.:..||.:|
Human   308 FSKDTLEKIDKARSEGLYHEVVKLCRECLEKQEPVFADTNIYMLRML--SIVSEVLSYLQAFEEA 370

  Fly   340 -----ALLTQYGPLLHPNHFML 356
                 .::..|..|.|||:..|
Human   371 SFYARRMVDGYMKLYHPNNAQL 392

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.