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Protein Alignment SmydA-7 and SMYD4

DIOPT Version :9

Sequence 1:	NP_001261039.1	Gene:	SmydA-7 / 36916	FlyBaseID:	FBgn0034182	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_443160.2	Gene:	SMYD4 / 114826	HGNCID:	21067	Length:	804	Species:	Homo sapiens

Alignment Length:	596	Identity:	123/596 - (20%)
Similarity:	193/596 - (32%)	Gaps:	187/596 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQEFGENIQHAH-------DEKLGRHLVASIAIEPGDTILEERPL--------LVAPH------W 44
            ::|..|.:.:|.       |...||.|||:..|.||:.:::|...        |..||      |
Human   221 LREENEQLSNASSSIGLCVDPLKGRCLVATKDILPGELLVQEDAFVSVLNPGELPPPHHGLDSKW 285

  Fly    45 ECH----QLKCAQCLQESY--VICRRCQVFPLC-MDCNQ-----HDEFEC--------------- 82
            :..    .|.|.:||:.:.  |.|..|.....| .:|.|     :...||
Human   286 DTRVTNGDLYCHRCLKHTLATVPCDGCSYAKYCSQECLQQAWELYHRTECPLGGLLLTLGVFCHI 350

  Fly    83 --------------EFFTSGAGKALCKDILVK---------NFGICGLLKLLLLLENP----RTK 120
                          :..|....|...|||.:.         |:|:....|...::|.|    ...
Human   351 ALRLTLLVGFEDVRKIITKLCDKISNKDICLPESNNQVKTLNYGLGESEKNGNIVETPIPGCDIN 415

  Fly   121 GDCQMLIDVPINLSDYRDGEGMWQEHE---ELVVRPL---MESGLADVLPTQ------------- 166
            |..:...:...||..:.:...  .||:   .|.|..|   :|:.....:||:
Human   416 GKYENNYNAVFNLLPHTENHS--PEHKFLCALCVSALCRQLEAASLQAIPTERIVNSSQLKAAVT 478

  Fly   167 -ELTSD------ALHAHCIRIDSN-----SFEVTAKDGDTL---------KGIFVWGATLPHHCV 210
             ||..|      |:..|.:::..|     :.:.|...|..:         .|||...:.|.|.|.
Human   479 PELCPDVTIWGVAMLRHMLQLQCNAQAMTTIQHTGPKGSIVTDSRQVRLATGIFPVISLLNHSCS 543

  Fly   211 PNTVVALDEQFNMKLYAAVPLQPGDIIYNSY--TNPLMGTSQRQHQLRLSRRLECICSRCLDPTE 273
            |||.|:..... ..:.|:..::.|..|.:.|  ....||.::||.:||.....:|.|..|  .||
Human   544 PNTSVSFISTV-ATIRASQRIRKGQEILHCYGPHKSRMGVAERQQKLRSQYFFDCACPAC--QTE 605

  Fly   274 -----MGTHMSSLKCKECPGFSVCEIDSNGKLGDWRCPDCRALLTAAEVHELQAAVGSALVDAMG 333
                 .|....:..|..|.  :..:.|...:.|...|.:             .|.....||..:.
Human   606 AHRMAAGPRWEAFCCNSCG--APMQGDDVLRCGSRSCAE-------------SAVSRDHLVSRLQ 655

  Fly   334 DLQ----VYEALLTQYGPL-----------------LHPNHFMLLDIKQNIASILRAAALMNSMD 377
            |||    |.:.||.. |.|                 |...|.::.:|...:|   ||.|.:....
Human   656 DLQQQVRVAQKLLRD-GELERAVQRLSGCQRDAESFLWAEHAVVGEIADGLA---RACAALGDWQ 716

  Fly   378 QPCKKLL-----------ARRVELCSDLLPVCRAVVPGIS---KLYAIGLFEYLLAL------VE 422
            :....|.           ...||:..:|..:.:....|.:   .|..|...|.:|:|      .|
Human   717 KSATHLQRSLYVVEVRHGPSSVEMGHELFKLAQIFFNGFAVPEALSTIQKAEEVLSLHCGPWDDE 781

  Fly   423 LVELQFAESDL 433
            :.|||..:|.|
Human   782 IQELQKMKSCL 792

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.