Sequence 1: | NP_477317.1 | Gene: | RhoGEF2 / 36915 | FlyBaseID: | FBgn0023172 | Length: | 2559 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_062645.2 | Gene: | Net1 / 56349 | MGIID: | 1927138 | Length: | 595 | Species: | Mus musculus |
Alignment Length: | 609 | Identity: | 126/609 - (20%) |
---|---|---|---|
Similarity: | 230/609 - (37%) | Gaps: | 162/609 - (26%) |
- Green bases have known domain annotations that are detailed below.
Fly 1358 PKHKSAPVSVNRSE------------SYKERLSNKR-----------------NRNSRRKTSDP- 1392
Fly 1393 SLSSRPNDEQLDLGLSNATYVGSSNSSLSSAGGSESPS----------TSMEHFAAPGAAGGVQV 1447
Fly 1448 PPMGLNQNQHPHLLIQQHAQQYCQQDSFQAGLAGAAGSSAASNSSFWNAGHPLPVARWTLESEDE 1512
Fly 1513 DDVNEADWSSMVAAEVLAALTDAEKKRQEIINEIYQTERNHVRTLKLLDRLFFLPLYESGLLSQD 1577
Fly 1578 HLLLLFP--PALLSLRE-IHGAFEQSLKQRRIEHNHVVNTIGDLLADMFDGQSGVVLCEFAAQFC 1639
Fly 1640 ARQQIALEALKEKRNKDEMLQKLLKKSESHKACRRLELKDLLPTVLQRLTKYPLLFENLYKVTVR 1704
Fly 1705 LLPENTTEAEAIQRAVESSKRILVEVNQAVKTAEDAHKLQNIQRKLDRSSY--DKEEFKKLDLTQ 1767
Fly 1768 HHLIHDGNLTIKKNPSVQLHGLLFENMIVL---LTKQDDKYYLKNLHTPLSITNKPVSPIMSIDA 1829
Fly 1830 DTL----IRQEAADKNSFFLIKMKTSQMLELRAPSSSECKTWFK-HFSDVAARQSKNRSKNASSN 1889
Fly 1890 HDTSISDPALAAIPHSNTKESLEL 1913 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
RhoGEF2 | NP_477317.1 | PDZ | 260..334 | CDD:214570 | |
RGS_GEF_like | 934..1055 | CDD:188710 | |||
C1_1 | 1151..1202 | CDD:278556 | |||
RhoGEF | 1539..1731 | CDD:238091 | 45/194 (23%) | ||
PH_RhoGEF | 1770..1875 | CDD:275411 | 22/112 (20%) | ||
DUF2413 | 2242..>2378 | CDD:287302 | |||
Net1 | NP_062645.2 | Necessary for nuclear localization | 1..74 | 12/60 (20%) | |
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..42 | 5/28 (18%) | |||
Nuclear localization signal | 12..19 | 2/5 (40%) | |||
Nuclear localization signal | 66..72 | 2/5 (40%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 127..151 | 8/33 (24%) | |||
RhoGEF | 178..354 | CDD:214619 | 42/191 (22%) | ||
PH_Net1 | 368..502 | CDD:270044 | 27/160 (17%) | ||
PH | 387..501 | CDD:278594 | 25/140 (18%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 555..595 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG5422 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |