Sequence 1: | NP_477317.1 | Gene: | RhoGEF2 / 36915 | FlyBaseID: | FBgn0023172 | Length: | 2559 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001003702.2 | Gene: | ARHGEF35 / 445328 | HGNCID: | 33846 | Length: | 484 | Species: | Homo sapiens |
Alignment Length: | 469 | Identity: | 97/469 - (20%) |
---|---|---|---|
Similarity: | 166/469 - (35%) | Gaps: | 123/469 - (26%) |
- Green bases have known domain annotations that are detailed below.
Fly 2094 PGEKLR---RLDASIRNDLLEKQKIICDIFRLPVEHYDQIVDIAMMPEAPKD-SADI-------- 2146
Fly 2147 ---------------ALAAYDQIQTLT-------KMLNEYMHVTP--------EQEVS-----AV 2176
Fly 2177 STAVCGHCHEKEKLRKKVAPSSSFSSSPPPLPPPNRQHAQAQA-------QIPPSRLMPKLQTLD 2234
Fly 2235 LDEVAIHED----DDGYCEIDELR--LPAIPSKPHERPTTPLAPFNTEPKTSQSVID------AS 2287
Fly 2288 KRQSTDAVPEGL----LEQEPLE----GDKTETKGEDNEVK-TVPSDKLSESCNEERQCVEADIT 2343
Fly 2344 KEVADPTTSKNEAAASVDE-LPSQSREIKTAEN-------ASKSVADKKEDNEETIEEGVASTVD 2400
Fly 2401 SSTQTSPTESPKETDKLTGGS---SSTCGPNRIQHASVLEPSVPCHALSSI---VTILNEQISML 2459
Fly 2460 LPKINERDMERERL 2473 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
RhoGEF2 | NP_477317.1 | PDZ | 260..334 | CDD:214570 | |
RGS_GEF_like | 934..1055 | CDD:188710 | |||
C1_1 | 1151..1202 | CDD:278556 | |||
RhoGEF | 1539..1731 | CDD:238091 | |||
PH_RhoGEF | 1770..1875 | CDD:275411 | |||
DUF2413 | 2242..>2378 | CDD:287302 | 34/164 (21%) | ||
ARHGEF35 | NP_001003702.2 | ARHGEF5_35 | 1..478 | CDD:317795 | 95/465 (20%) |
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 139..418 | 57/291 (20%) | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG5422 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 0 | 0.000 | Not matched by this tool. | |||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.900 |