| Sequence 1: | NP_477317.1 | Gene: | RhoGEF2 / 36915 | FlyBaseID: | FBgn0023172 | Length: | 2559 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001364258.1 | Gene: | PLEKHG7 / 440107 | HGNCID: | 33829 | Length: | 691 | Species: | Homo sapiens |
| Alignment Length: | 554 | Identity: | 120/554 - (21%) |
|---|---|---|---|
| Similarity: | 206/554 - (37%) | Gaps: | 187/554 - (33%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1361 KSAPVSVNRSESYKERLSNKRNRNSRRKTSDPSLS----------SRPNDEQLDLGLSNATYVGS 1415
Fly 1416 SNSSLSSAGGSESPSTSMEHFAAPGAAG---------------------GVQVPP---------- 1449
Fly 1450 -----------------------MGLNQNQHPHLLIQQHAQQYCQQDSFQA----GLAGAAGSSA 1487
Fly 1488 ASNSSFWN----AGHPLPVARWTLESEDEDDVNEADWSSMVAAEVLAALTDAEKKRQEIINEIYQ 1548
Fly 1549 TE----RNHVRTLKL--LDRLFFLPLYESGLLSQDHLLLLFPPALLSLREIHGAFEQSL---KQR 1604
Fly 1605 RIEHNHVVNTIG--DLLADMFDGQSGVVLCEFAAQFCARQQIALEALKEKRNKDEMLQKLLKKSE 1667
Fly 1668 SHKACRRLELKDLLPTVLQRLTKYPLLFENLYKVTVRLLPENTTEAEAIQRAVESSKRILV---- 1728
Fly 1729 -EVNQAVKTAEDAHK-LQNIQ--RKLDR-----SSYDKEE-----------FKK------LDLTQ 1767
Fly 1768 HHLIHDGNLTIKKNPS-VQLHGLLFENMIVLLTK 1800 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| RhoGEF2 | NP_477317.1 | PDZ | 260..334 | CDD:214570 | |
| RGS_GEF_like | 934..1055 | CDD:188710 | |||
| C1_1 | 1151..1202 | CDD:278556 | |||
| RhoGEF | 1539..1731 | CDD:238091 | 54/207 (26%) | ||
| PH_RhoGEF | 1770..1875 | CDD:275411 | 10/32 (31%) | ||
| DUF2413 | 2242..>2378 | CDD:287302 | |||
| PLEKHG7 | NP_001364258.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..48 | ||
| DUF4675 | 2..178 | CDD:406211 | 24/99 (24%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 109..140 | 8/30 (27%) | |||
| RhoGEF | 292..476 | CDD:214619 | 53/208 (25%) | ||
| PH_PLEKHG7 | 535..663 | CDD:270065 | 11/33 (33%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG5422 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||