| Sequence 1: | NP_477317.1 | Gene: | RhoGEF2 / 36915 | FlyBaseID: | FBgn0023172 | Length: | 2559 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_056574.2 | Gene: | Fgd3 / 30938 | MGIID: | 1353657 | Length: | 733 | Species: | Mus musculus |
| Alignment Length: | 736 | Identity: | 151/736 - (20%) |
|---|---|---|---|
| Similarity: | 254/736 - (34%) | Gaps: | 209/736 - (28%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1403 LDLGLSNATYVGSSNSSLS--SAGGSESPSTSMEHF-AAPGAAGGV--QVPPMGLNQNQHPHLLI 1462
Fly 1463 QQHAQQYCQQDSFQAGLAGAAGSSAASN-----SSFWNAGHPLPVARWTLESE-------DEDDV 1515
Fly 1516 NEADWSSM----------VAAEVLAALTDAE--KKRQEIINEIYQTERNHVRTLKLLDRLFFLPL 1568
Fly 1569 YESGLLSQDHLLLLFPPA---------LLSLREIHGAFEQSLKQRRIEHNHVVN-TIGDLLADMF 1623
Fly 1624 DGQSGVVLCEFAAQFCARQQIALEALKEKRNKDEMLQKLLKKSESHKACRRLELKDLLPTVLQRL 1688
Fly 1689 TKYPLLFENLYKVTVRLLPENTTEAEAIQRAVESSKRILVEVNQAVKTAEDAHKLQNIQRKLDRS 1753
Fly 1754 SYDKEEFKKLDLTQ--HHLIHDGN---LTIKKNPSVQLHGLLFENMIVLLTKQDDKYYLKNLHTP 1813
Fly 1814 LSITNKPVSPIMSIDADTLIRQEAADKNSFFLIKMKTSQMLELRAPSSSECKTWFKHF-SDVAAR 1877
Fly 1878 QSKNRSKNASSNHDTSISDPALAAIPHSNTKESLELSTDTVQPLAATATLTTTPLAPMLPIATVT 1942
Fly 1943 PAPATNNSNVSSLTGVQLRNPQRDATASESDADYVNTPKPRSSQNEVNRTMSIRSTGEPIQKYSA 2007
Fly 2008 NGTEANDVTLRHSQSTRESVRPG--STGEERNSTYGMVGGNSKRD-----SASIVC--------- 2056
Fly 2057 -SNNSNNTRTLLMQSPLVDPT 2076 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| RhoGEF2 | NP_477317.1 | PDZ | 260..334 | CDD:214570 | |
| RGS_GEF_like | 934..1055 | CDD:188710 | |||
| C1_1 | 1151..1202 | CDD:278556 | |||
| RhoGEF | 1539..1731 | CDD:238091 | 40/201 (20%) | ||
| PH_RhoGEF | 1770..1875 | CDD:275411 | 25/108 (23%) | ||
| DUF2413 | 2242..>2378 | CDD:287302 | |||
| Fgd3 | NP_056574.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..134 | 37/144 (26%) | |
| RhoGEF | 156..335 | CDD:238091 | 40/199 (20%) | ||
| PH-like | 367..474 | CDD:418428 | 27/117 (23%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 481..535 | 18/140 (13%) | |||
| FYVE_FGD3 | 527..580 | CDD:277279 | 14/59 (24%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 586..612 | 2/4 (50%) | |||
| PH2_FGD1-4 | 606..710 | CDD:270056 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 712..733 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG5422 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||