| Sequence 1: | NP_477317.1 | Gene: | RhoGEF2 / 36915 | FlyBaseID: | FBgn0023172 | Length: | 2559 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_663494.2 | Gene: | Farp2 / 227377 | MGIID: | 2385126 | Length: | 1065 | Species: | Mus musculus |
| Alignment Length: | 760 | Identity: | 163/760 - (21%) |
|---|---|---|---|
| Similarity: | 264/760 - (34%) | Gaps: | 237/760 - (31%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1353 RYSQHPKHKSAPVSVNRSESYK------------------ERLSNKRNRNSRRKTS--------- 1390
Fly 1391 ------------DPSLSSR-------PNDEQLDLGLSNATYVGSSNSSL---------------- 1420
Fly 1421 SSAGGSESPSTSMEHFAA-----PGAAGGVQVP---PMGLNQNQHPHLLIQQHAQQYCQQDSFQA 1477
Fly 1478 GLAGA-AGSSAASNSSFWNAGHPLPVARWTLESEDEDDVNEADWSSMVAAEVLAALTDAEKKRQE 1541
Fly 1542 IINEIYQTERNHVRTLKLLDRLFFLPLYESGLLSQDHLLLLFPPALLSL--------REIHGAFE 1598
Fly 1599 QSLKQR----------RIEHNHVVNTIGD-LLADMFDGQSGVVLCEFAAQFCARQQIALEALKEK 1652
Fly 1653 RNKD-EMLQKLLKKSESHKACRRLELKDLLPTVLQRLTKYPLLFENLYKVTVRLLPENTTEAEAI 1716
Fly 1717 QRAVESSKRILVEVNQAVKTAEDAHKLQNIQRKLDRSSYDKEEFKKLDLTQHHLIHDGNL-TIKK 1780
Fly 1781 NPSVQLHGLLFENMIVLLTKQDDKYYLKNLHTPLSITN------KPVSPIMSIDADTLIRQEAAD 1839
Fly 1840 KNSF---FLIKMKTSQMLELRAPSSSECKTWFKHFSDVAARQSKNRSKNASSNHDTSISDPALAA 1901
Fly 1902 IPHSNTKESLELSTDTVQPLAATATLTTTPLAPMLPIATVTPAPATNNSNVSSLTGVQLRNPQRD 1966
Fly 1967 ATASESDADYVNTPKPRSSQN-EVNRTMSIRSTGEPIQKY-SANG 2009 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| RhoGEF2 | NP_477317.1 | PDZ | 260..334 | CDD:214570 | |
| RGS_GEF_like | 934..1055 | CDD:188710 | |||
| C1_1 | 1151..1202 | CDD:278556 | |||
| RhoGEF | 1539..1731 | CDD:238091 | 50/211 (24%) | ||
| PH_RhoGEF | 1770..1875 | CDD:275411 | 20/114 (18%) | ||
| DUF2413 | 2242..>2378 | CDD:287302 | |||
| Farp2 | NP_663494.2 | B41 | 45..234 | CDD:214604 | |
| FERM_N | 48..111 | CDD:286467 | |||
| FERM_M | 131..234 | CDD:278785 | |||
| FERM_C_FARP1-like | 221..341 | CDD:270014 | 7/19 (37%) | ||
| FA | 333..375 | CDD:285894 | 7/42 (17%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 406..489 | 19/89 (21%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 504..534 | 7/33 (21%) | |||
| RhoGEF | 540..723 | CDD:238091 | 53/224 (24%) | ||
| PH1_FARP1-like | 752..859 | CDD:269928 | 24/131 (18%) | ||
| PH | 760..854 | CDD:278594 | 21/115 (18%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 874..902 | 11/62 (18%) | |||
| PH2_FARP1-like | 929..1026 | CDD:270055 | 6/22 (27%) | ||
| PH | 934..1027 | CDD:278594 | 5/17 (29%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||