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Protein Alignment CG8963 and TIF4631

DIOPT Version :9

Sequence 1:	NP_001163171.1	Gene:	CG8963 / 36913	FlyBaseID:	FBgn0034181	Length:	559	Species:	Drosophila melanogaster
Sequence 2:	NP_011678.3	Gene:	TIF4631 / 853071	SGDID:	S000003394	Length:	952	Species:	Saccharomyces cerevisiae

Alignment Length:	524	Identity:	93/524 - (17%)
Similarity:	185/524 - (35%)	Gaps:	135/524 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 SDASNLSATAT-IFIPRGAAPPQQQSRHQQYQQAGGAGGGAPYGQQQPRYVNGFKHHHQQHHQQP 131
            :||..:.:||: |.||.|      ..|..:.:.:|..|..:..|
Yeast   468 ADAEWVQSTASKIVIPPG------MGRGNRSRDSGRFGNNSSRG--------------------- 505

  Fly   132 HYNHHHNHQQKFNNDMQKLTNSVQNRLHLNSQQGSAGNYYQQQQVHQNTHHHQQHQQQHQPHNQH 196
             ::..:...:..::.....|:|.:....:|..:.|..:|..::...:.::.:::.::..:|..:.
Yeast   506 -HDFRNTSVRNMDDRANSRTSSKRRSKRMNDDRRSNRSYTSRRDRERGSYRNEEKREDDKPKEEV 569

  Fly   197 AKFQRHFHLNNSFQQIVQQTQHNQPQQPHHQQHNQQQQQYIQNQNQQPQPSTSTAAASSSSSNSS 261
            |                       |..|   ..|:...::                .|..:....
Yeast   570 A-----------------------PLVP---SANRWVPKF----------------KSKKTEKKL 592

  Fly   262 QPDMATIALEYLD---------TVIHCLNQNPGQFDSIASRFLTI--FDGMENNQFVLSIAMEDI 315
            .||..|   |.||         ::::.|...  .||:|:|..|.|  ....|.|...|...:|.|
Yeast   593 APDGKT---ELLDKDEVERKMKSLLNKLTLE--MFDAISSEILAIANISVWETNGETLKAVIEQI 652

  Fly   316 FEKSIEQPNFRYMGAKLY-NLLHMLN-----------SKPDSLFHTLL-KCKLDYHQEEVTKYMR 367
            |.|:.::|::..|.|:|. .::..||           :.|..:.|.|: :|..::.:....| :.
Yeast   653 FLKACDEPHWSSMYAQLCGKVVKELNPDITDETNEGKTGPKLVLHYLVARCHAEFDKGWTDK-LP 716

  Fly   368 SNEQQKVRETALFLAELY----MQLRGDDDSRIQLIA-VNIVYSLSKLLASESNENVRCLCQTLK 427
            :||.....|..:...|.|    .:.||     :.|:. :..:|.|:.|......|   |..:.:|
Yeast   717 TNEDGTPLEPEMMSEEYYAAASAKRRG-----LGLVRFIGFLYRLNLLTGKMMFE---CFRRLMK 773

  Fly   428 LAGYDLTADCPKD--IQEIITALQAIELKSPGKYPMAASVIALQQNNWGRKVSNALGDDEDTVKE 490
                ||| |.|.:  ::.::..|..:     |:.....|....|....|.::.::|....|.:.:
Yeast   774 ----DLT-DSPSEETLESVVELLNTV-----GEQFETDSFRTGQATLEGSQLLDSLFGILDNIIQ 828

  Fly   491 PPRLSDEPVFYGPDGRELTAEETDFLAGGDNDGDDDFDGDGADLEIDAEMDEETERAYKEFCKQG 555
            ..::|....|...|.:||.         .|.:.:.|...:|.........:||.:|..|...:..
Yeast   829 TAKISSRIKFKLIDIKELR---------HDKNWNSDKKDNGPKTIQQIHEEEERQRQLKNNSRSN 884

  Fly   556 KQKT 559
            .::|
Yeast   885 SRRT 888

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.