DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8963 and eif4g1a

DIOPT Version :9

Sequence 1:	NP_001163171.1	Gene:	CG8963 / 36913	FlyBaseID:	FBgn0034181	Length:	559	Species:	Drosophila melanogaster
Sequence 2:	XP_009296603.1	Gene:	eif4g1a / 572435	ZFINID:	ZDB-GENE-070112-702	Length:	1640	Species:	Danio rerio

Alignment Length:	408	Identity:	81/408 - (19%)
Similarity:	135/408 - (33%)	Gaps:	139/408 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   183 HQQHQQQHQPHNQHAK--FQRHFHLNNSFQQIVQQTQHNQPQQPH-------------------- 225
            :|..::|.:|.|...|  :.|.|.|...|   :..:.|.....||
Zfish   628 YQYKEEQWKPINPEEKKRYDREFLLGFQF---ISASMHKPEGLPHISDVVLDKANKTPLRPLDPR 689

  Fly   226 -------------------------------HQQHNQQQQQYIQNQ--------------NQQPQ 245
                                           ..|..:.:.|..:|.              ||...
Zfish   690 SLMNCGPDFTPSYANLGRQSSGGGGRGPSARRPQPGRGKDQISRNPKIITSVSLKDNIELNQAEN 754

  Fly   246 PSTSTAAASSSSSNSSQPDMATIA--LEYLDTVIHCLNQ-NPGQFDSIASRFLTI-FDGMENNQF 306
            ..|.:......|....:.|.|..|  .|....|...||: .|..|..:..:...: .|..|..:.
Zfish   755 AWTPSVKKQVRSRGEEEEDDAEAAKTQELFRRVRSVLNKLTPQMFQQLMKQVTELAIDTEERLKG 819

  Fly   307 VLSIAMEDIFEKSIEQPNFRYMGAKLYNLLHML----NSKP------------------------ 343
            |:.:    ||||:|.:|||....|.:...|..|    :.||
Zfish   820 VIDL----IFEKAISEPNFSVAYANMCRCLMGLKVPTSDKPGVTVNFRKLLLNRCQKEFEKDKDD 880

  Fly   344 DSLFHTLLKCKLDYHQEEVTKYMRSNEQQ----KVRETAL----FLAELYMQLRGDDDSRIQLIA 400
            |.:|....| :||...||..:...::|.|    |.|:.:|    |:.||:         :::::.
Zfish   881 DEIFEQKQK-ELDAATEEEERQRLNDELQDAKDKARKRSLGNIKFIGELF---------KLKMLT 935

  Fly   401 VNIVYS-LSKLLASESNENVRCLCQTLKLAGYDLTADCPK--------DIQEIITALQAIELKSP 456
            ..|::. :.|||.:...:::.|||:.|...|.||..:..|        .:::||.     |.|:.
Zfish   936 EPIMHDCIVKLLKNHDEDSLECLCRLLSTIGKDLDFEKAKPRMDQYFHQMEKIIK-----EKKTS 995

  Fly   457 GKYP-MAASVIALQQNNW 473
            .:.. |...|:.|::|||
Zfish   996 SRIRFMLQDVLDLRKNNW 1013

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8963	NP_001163171.1	MIF4G	270..472	CDD:214713	56/249 (22%)
eif4g1a	XP_009296603.1	MIF4G	784..1012	CDD:280935	55/246 (22%)
		MA3	1285..1395	CDD:280933
		W2_eIF4G1_like	1482..1611	CDD:211397
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910