DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8963 and eif4g3b

DIOPT Version :9

Sequence 1:	NP_001163171.1	Gene:	CG8963 / 36913	FlyBaseID:	FBgn0034181	Length:	559	Species:	Drosophila melanogaster
Sequence 2:	XP_021325628.1	Gene:	eif4g3b / 568761	ZFINID:	ZDB-GENE-090312-49	Length:	1733	Species:	Danio rerio

Alignment Length:	288	Identity:	64/288 - (22%)
Similarity:	120/288 - (41%)	Gaps:	70/288 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   256 SSSNSSQPDM----------ATIALEYLDTVIHCLNQ-NPGQFDSIASRF--LTIFDGMENNQFV 307
            ::.|:.:|.|          |....|....|...||: .|..|..:..:.  ||| |..|..:.|
Zfish   876 TTENAWKPGMKREGAVEDPDAQRTQELFRKVRSILNKLTPQMFSQLMKQVTDLTI-DTEERLKGV 939

  Fly   308 LSIAMEDIFEKSIEQPNFRY----MGAKLYNLLHMLNSKPDSL--FHTLL--KCKLDYHQE---- 360
            :.:    :|||:|.:|:|..    |.:.|..|...:..||:|.  |..||  :|:.::.::
Zfish   940 IDL----VFEKAINEPSFSVAYGNMCSCLATLKVPMTDKPNSTVNFRKLLLNRCQKEFEKDKMDD 1000

  Fly   361 --------EVTKYMRSNEQQKVRE---------------TALFLAELYMQLRGDDDSRIQLIAVN 402
                    |:.....|:|:::::|               ...|:.||:         :::::...
Zfish  1001 DAFEKKHRELEAATASSERERLQEELEEAKDKARRRSIGNIKFIGELF---------KLRMLTEA 1056

  Fly   403 IVYS-LSKLLASESNENVRCLCQTLKLAGYDLTADCPKD-IQEIITALQAI--ELKSPGKYP-MA 462
            |::. :.|||.:...|::.|||:.|...|.||..:..|. :.:....::.|  |.|:..:.. |.
Zfish  1057 IMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIVKERKTSSRIRFML 1121

  Fly   463 ASVIALQQNNWGRKVSNALGDDEDTVKE 490
            ..||.|:.:||   ||........|:::
Zfish  1122 QDVIDLRLHNW---VSRRADQGPKTIEQ 1146

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8963	NP_001163171.1	MIF4G	270..472	CDD:214713	55/244 (23%)
eif4g3b	XP_021325628.1	Atrophin-1	<59..632	CDD:331285
		MIF4G	903..1131	CDD:280935	54/241 (22%)
		MA3	1371..1482	CDD:280933
		W2_eIF4G1_like	1569..1704	CDD:211397
		W2	<1683..1729	CDD:327369
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910