Protein Alignment Paip1 and Paip1

DIOPT Version :10

• Sequence 1: NP_611180.1
• Gene: Paip1 / 36913
• FlyBaseID: FBgn0034181
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_663432.1
• Gene: Paip1 / 218693
• MGIID: 2384993
• Length: 400
• Species: Mus musculus
• Alignment Length: 409
• Identity: 106/409 - (25%)
• Similarity: 187/409 - (45%)
• Gaps: 67/409 - (16%)

  Fly   205 LNNSFQQIVQQTQHNQPQQPHHQQHNQQQQQYIQNQNQQPQPSTSTAAASSSSSNSSQ------- 262
            :::||.:..:||   :||:......::..||..::...:||...:....|..|:|:.:
Mouse     1 MSDSFDRAPEQT---KPQRAPPSSQDKIPQQNSESAMAKPQVVVAPVLMSKLSANAPEFYPSGYS 62

  Fly   263 -----------PDMATIALEYLDTVIHCLNQNPGQFDSIASRFLTIFDGMENNQFVLSIAMEDIF 316
                       .|..|:: ||:...::.|.:.||.|::...:|....:|.......|...:|.|:
Mouse    63 SNYTESYEDGCEDYPTLS-EYVQDFLNHLTEQPGSFETEIEQFAETLNGWVTTDDALQELVELIY 126

  Fly   317 EKSIEQPNFRYMGAKLYNLL-HMLNSKPDS-LFHTLL--KCKLDYHQ-------EEVTKYMRSNE 370
            :::...|||.||||:|.|.| |.|...|.| .|..||  :|:.:|..       :|||:
Mouse   127 QQATSIPNFSYMGARLCNYLSHHLTISPQSGNFRQLLLQRCRTEYEAKDQAAKGDEVTR------ 185

  Fly   371 QQKVRETALFLAELY--MQLRGDDD--SRIQLIAVNIVYSLSKLLASESNENVRCLCQTLKLAGY 431
             ::.....|||.|||  ::::|.:.  :|..::.|.:...|:.|.::..::|:.|..:.|||.|
Mouse   186 -KRFHAFVLFLGELYLNLEIKGTNGQVTRADILQVGLRELLNALFSNPMDDNLICAVKLLKLTG- 248

  Fly   432 DLTADCPK-----DIQEIITALQAIELK---SPGKYPMAASVIALQQNNWGRKVSNALGDDEDTV 488
            .:..|..|     |::|||..::.:.|.   |.....|...::.|:.:||||..:.:...:....
Mouse   249 SVLEDTWKEKGKTDMEEIIQRIENVVLDANCSRDVKQMLLKLVELRSSNWGRVHATSTYREATPE 313

  Fly   489 KEPPRLSDEPVFYGPDGRELTAEETDFLAGGD-----NDGDDDFDGDGADL---------EIDAE 539
            .:|....:||.||..||...||.:.|:.....     .|...|::.:|.||         :||.|
Mouse   314 NDPNYFMNEPTFYTSDGVPFTAADPDYQEKYQELLEREDFFPDYEENGTDLSGAGDPYLDDIDDE 378

  Fly   540 MDEETERAYKEFCKQGKQK 558
            ||.|.|.||::||.:.::|
Mouse   379 MDPEIEEAYEKFCLESERK 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Paip1	NP_611180.1	MIF4G	270..472	CDD:214713	60/224 (27%)
Paip1	NP_663432.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..36		8/34 (24%)
		PABPC1-interacting motif-2 (PAM2). /evidence=ECO:0000250|UniProtKB:Q9H074	37..64		6/44 (14%)
		PAIP1 middle domain (PAIP1M). /evidence=ECO:0000250|UniProtKB:Q9H074	78..296		64/240 (27%)
		MIF4G	81..297	CDD:397130	63/238 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	356..376
		PABPC1-interacting motif-1 (PAM1). /evidence=ECO:0000250|UniProtKB:Q9H074	361..400