Protein Alignment Ehbp1 and actn1

DIOPT Version :9

• Sequence 1: NP_995865.2
• Gene: Ehbp1 / 36912
• FlyBaseID: FBgn0034180
• Length: 1141
• Species: Drosophila melanogaster
• Sequence 2: XP_012824128.1
• Gene: actn1 / 780123
• XenbaseID: XB-GENE-493909
• Length: 912
• Species: Xenopus tropicalis
• Alignment Length: 779
• Identity: 169/779 - (21%)
• Similarity: 284/779 - (36%)
• Gaps: 208/779 - (26%)

  Fly   432 SIGSCFSTSGSLNNSLKPVEKIVLK---------ENTPGQDLLEWCKEVTKDYPNVKVTNLTTSW 487
            |||:.....|:...:|..:..|:|:         |.:..:.||.||:..|..|.||.:.|...||
 Frog   107 SIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISW 171

  Fly   488 RNGMAFCAIIHHFVPELIDMSKLSAHDVVGNCRIGFDAAES-LGIPRVIEPRDMNMLTVPDKLAV 551
            ::|:.|||:||...|||||..||...|.:.|....||.||. |.||::::..|:.....||:.|:
 Frog   172 KDGLGFCALIHRHRPELIDYGKLRKDDPLTNLNTAFDVAERYLDIPKMLDAEDIVGTARPDEKAI 236

  Fly   552 MTYLHQLRAHFTGKQL------KIEQIGSTADESSYVIGDYK---SDNLS---------QNRINF 598
            |||:......|:|.|.      :|.::.:...|:..::.||:   ||.|.         :||.
 Frog   237 MTYVSSFYHAFSGAQKAETAANRICKVLAVNQENEQLMEDYEKLASDLLEWIRRTIPWLENRA-- 299

  Fly   599 SHPKSLLLHQNSFDEEINGSNKSEQLSPTSKKDVKNLILYNSKNILDKVLSPTKDKNSINASQHA 663
              |::.:   .:..:::.......:|....|...|..:..|...:      .||.:.|...:...
 Frog   300 --PENTM---QAMQQKLEDFRDYRRLHKPPKVQEKCQLEINFNTL------QTKLRLSNRPAFMP 353

  Fly   664 NQSPMLSCQTTPPQDESLDKGSQPGGKENSSITTIDPQAASEERQQRLLEQARRL----ILETRV 724
            ::..|:|           |..:..||.|.          |.:..::.:|.:.|||    .|..:.
 Frog   354 SEGKMVS-----------DINNAWGGLEQ----------AEKGYEEWMLNEIRRLERLDHLAEKF 397

  Fly   725 KSGGSI-ESPTRPK---LER------TISPI------HNGAEEFYAEHAKKLELKEPGSPSHRLS 773
            :...|| |:.|..|   |::      ::|.|      |...|...|.|..::|  :..:.:..|:
 Frog   398 RQKASIHEAWTDGKEAMLQKKDYETASLSDIKALLKKHEAFESDLAAHQDRVE--QIAAIAQELN 460

  Fly   774 --DPKVLQSFNAIVERVSPKHEKRGDKLSYIDSELEALEREQ---EAIDQKASNLEAKLRAVMGG 833
              |....|:.||..:|:..:.:..|   :......|||||.:   |.|||  ..||...||.
 Frog   461 ELDYYDSQTVNARCQRICDQWDNLG---ALTQQRREALERTEKLLETIDQ--LYLEYAKRAA--- 517

  Fly   834 NPSNNRRGGARN--SNPFLRLIRNSIGG----GDVIRIKLLDSDDE--SLFGGGAGSGGGRSGAC 890
             |.||...||..  .:.|:......|.|    .:..:..|.::|.|  ::.|            .
 Frog   518 -PFNNWMEGAMEDLQDTFIVHTIEEIQGLTTAHEQFKATLPEADKERQAILG------------I 569

  Fly   891 SEDDDRDTSSDSVCNSGDELHTRLRPRPRSHSCFVNKNHQSTINTPAHLRPHHVHHVVPYTHMLD 955
            ..:..:...:..|..||...:|.:.|:              .||.    :..||..:||
 Frog   570 QNEISKIMQTYHVNMSGSNPYTSITPQ--------------EINN----KWDHVRQLVP------ 610

  Fly   956 SSPSALSSQQSSCDNLPACSDDDEVLAVAANGRAASLRRQQ---DRHRRRRQRRERRSHLCHTPN 1017
                                                 ||.|   :.|.|::|....|.......|
 Frog   611 -------------------------------------RRDQALTEEHARQQQNERLRKQFAAQAN 638

  Fly  1018 ------HCETEETEEQLLSQWFTLVNKKNALLRRQMQLNILEQE---KDLERKYTMLNQELRAAQ 1073
                  ..:.:|.....:....||.::.|.|  ||.:.:|:..:   ..||..:..:.:.|
 Frog   639 VIGPWIQTKMQEIGRIAIEMHGTLEDQLNNL--RQYEKSIVNYKPKIDQLESDHQQIQEAL---- 697

  Fly  1074 SVEDWRKTEVQREKERLLLEELMTIVDKRDQLVQHLHNQ-------EIAIEDDQEIARKLEHVD 1130
             :.|.:.|....|..|:..|:|:|.:.:   .:..:.||       .|:.|...|......|.|
 Frog   698 -IFDNKHTNYTMEHIRVGWEQLLTTIAR---TINEVENQVLTRDAKGISQEQMNEFRNSFSHFD 757

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ehbp1	NP_995865.2	NT-C2	12..165	CDD:287345
		CH	460..562	CDD:237981	40/102 (39%)
		DUF3585	<1027..1122	CDD:288945	21/104 (20%)
actn1	XP_012824128.1	SAC6	27..>290	CDD:227401	58/182 (32%)
		Spectrin	272..379	CDD:334073	22/140 (16%)
		SPEC	393..620	CDD:238103	60/310 (19%)
		Spectrin	632..730	CDD:334073	19/107 (18%)
		PTZ00184	738..>869	CDD:185504	5/20 (25%)
		EFhand_Ca_insen	842..908	CDD:312305

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910