DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ehbp1 and Smtnl1

DIOPT Version :9

Sequence 1:NP_995865.2 Gene:Ehbp1 / 36912 FlyBaseID:FBgn0034180 Length:1141 Species:Drosophila melanogaster
Sequence 2:NP_077192.1 Gene:Smtnl1 / 68678 MGIID:1915928 Length:459 Species:Mus musculus


Alignment Length:400 Identity:100/400 - (25%)
Similarity:158/400 - (39%) Gaps:115/400 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   253 DADGKREAANKL-------DLPTAASGGSSGAEESLKTPNGLQHVVDQTPIKSPDEVKQPKQTPV 310
            :|.||.||...|       :..||||...:|.:|..|              ..|:||::.::..:
Mouse    84 EARGKDEAQGDLAEEKVGKEDTTAASQEDTGKKEETK--------------PEPNEVREKEEAML 134

  Fly   311 ESLRSKTNEDFDKMVTSTPLE----PNVNKDDVKPKKKRAL--------FFTEKEDEQDLRVESV 363
            .|.:.|.:|      ..|.||    .:|| |..||:.|...        ..||.::|.|::.::.
Mouse   135 ASEKQKVDE------KETNLESKEKSDVN-DKAKPEPKEDAGAEVTVNEAETESQEEADVKDQAK 192

  Fly   364 KE-----------DTTKTIGDNSTTKEKPKEESQSSKDASSVV---------VPSAKRPELQPLN 408
            .|           ||.:.:...|.|:|:.:.:...|::.::|:         .|:.:.|.|.|..
Mouse   193 PELPEVDGKETGSDTKELVEPESPTEEQEQGKENESEERAAVIPSSPEEWPESPTDEGPSLSPDG 257

  Fly   409 LKKSYEPSQTPESAP---------VPAS----------------------------------VIN 430
            |    .|..|.|::|         ||.|                                  .|.
Mouse   258 L----APESTGETSPSASESSPSEVPGSPTEPQPSEKKKDRAPERRVSAPSRPRGPRAQNRKAIM 318

  Fly   431 ESIGSCFSTSGSLNNSLKPVEKIV--LKENTPGQDLLEWCKEVTKDYPNVKVTNLTTSWRNGMAF 493
            :..|...|...:|..:.|.....:  :|..     |||||:.:|::|.:|.:.|.::||.:||||
Mouse   319 DKFGGAASGPTALFRNTKAAGAAIGGVKNM-----LLEWCRAMTRNYEHVDIQNFSSSWSSGMAF 378

  Fly   494 CAIIHHFVPELIDMSKLSAHDVVGNCRIGFDAAESLG-IPRVIEPRDMNMLTVPDKLAVMTYLHQ 557
            ||:||.|.||..|.::|.......|..:.|..||.|. ..:::|..||..|.|||...|.||:.:
Mouse   379 CALIHKFFPEAFDYAELDPAKRRHNFTLAFSTAEKLADCAQLLEVDDMVRLAVPDSKCVYTYIQE 443

  Fly   558 LRAHFTGKQL 567
            |......|.|
Mouse   444 LYRSLVQKGL 453

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ehbp1NP_995865.2 NT-C2 12..165 CDD:287345
CH 460..562 CDD:237981 40/102 (39%)
DUF3585 <1027..1122 CDD:288945
Smtnl1NP_077192.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..314 52/254 (20%)
MDN1 <51..229 CDD:227596 38/165 (23%)
PTZ00449 <150..>310 CDD:185628 30/164 (18%)
CH 345..446 CDD:366016 41/105 (39%)
Calmodulin-binding 441..459 2/12 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167839257
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.840

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