Protein Alignment Ehbp1 and ehbp1

DIOPT Version :10

• Sequence 1: NP_995865.2
• Gene: Ehbp1 / 36912
• FlyBaseID: FBgn0034180
• Length: 1141
• Species: Drosophila melanogaster
• Sequence 2: XP_005158588.2
• Gene: ehbp1 / 560857
• ZFINID: ZDB-GENE-091006-4
• Length: 1274
• Species: Danio rerio
• Alignment Length: 1350
• Identity: 409/1350 - (30%)
• Similarity: 615/1350 - (45%)
• Gaps: 285/1350 - (21%)

  Fly     1 MASVWKRLQRNFKRAAKFQFTASYHDLHLETTAKWRPSNLSIVWTRRSRRVASAPLPWEPDMMNP 65
            ||||||||||..|.|:||||.|||.:|.:|.|.||:|..|.:||||||||.:|....|:|.:.||
Zfish     1 MASVWKRLQRVGKHASKFQFVASYQELMVECTKKWQPDKLVVVWTRRSRRKSSKSHSWQPGIKNP 65

  Fly    66 LVGNISWPVPDNHTISVTLFKDPRTHELEDKDWTFVIEDVTPMGKKRVLANASINMRKYASIEST 130
            ..|.:.||||:|..|:|||||||...|.|||:||||||:.:|.|:::.||.:.|||::|||...|
Zfish    66 YRGVVVWPVPENIEITVTLFKDPHAEEFEDKEWTFVIENESPSGRRKALATSCINMKQYASAMPT 130

  Fly   131 QQSFTLSLKPVSKKITAASLELTISCVFLREGKATDEDMQSVVSMMSVNNNDVAPLDDLEDIPDL 195
            |....|..||:|||:.:|:|:.::||:||||||||||||||:.|:||:...|:..|||.|:..:.
Zfish   131 QTDVKLKFKPLSKKVVSATLQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEENEE 195

  Fly   196 DGFSEITD-----NFNDFTQQLEHMTTSLNGCIDVATPQS--VPSLSEDPTPLAESFNPLHFELD 253
            |..:.:..     ...:..:||..: :|::|..|....|:  ..|.||:   |....|.|..| |
Zfish   196 DEENRVNQEEKAAKITEIVRQLNAL-SSIDGDPDDCLKQANKAASSSEE---LISKLNFLDQE-D 255

  Fly   254 ADGKREAANKLDLPTAASGGSSGAEESLKTPNGLQHVVDQTPIKSPDEVKQP----KQTPVESLR 314
            .|....:.|..|.|......:...:.....|:...||  |..||..|....|    ::...|...
Zfish   256 QDQSNMSCNPFDEPNDPDDLNPFGDPDEDEPSPQPHV--QPTIKDQDAPDCPFNPFEEADTEPDS 318

  Fly   315 SKTNEDFDKMVTSTPLEPNVN------KDDVKPKKKRALFF--TEKEDEQDLRVESVKEDTTKTI 371
            |:....||:.......:|.|:      :.:|:|.......:  |.:.:|::|. ||......:..
Zfish   319 SQYENPFDEPEPEPEPQPKVSPPRSSKRKNVRPVDMSKYLYANTTRTEEEELD-ESNPFYEPRLS 382

  Fly   372 GDNSTTKEK---------PKEESQSSKDASSVVVPSAKRPE-------LQPLNLKKSYE---PSQ 417
            |.:|:|.||         |......|.......:|....||       |.|..|.....   .|.
Zfish   383 GSDSSTLEKSMKRRAPQPPSAGPNLSVTPGPTPIPKTSSPEGTSTPPALAPSVLTAVIGRELASS 447

  Fly   418 TPESAPVPASVINESIGSCFSTSGSLNNSLKPVEKIVLKENTPGQDLLEWCKEVTKDYPNVKVTN 482
            :|:.:|:|:.|:.....:|.|                         ||.||:||||||..|::||
Zfish   448 SPKPSPIPSPVLGGRPNACSS-------------------------LLAWCREVTKDYRGVRITN 487

  Fly   483 LTTSWRNGMAFCAIIHHFVPELIDMSKLSAHDVVGNCRIGFDAAESLGIPRVIEPRDMNMLTVPD 547
            .|||||||:||||::|||.|:.||...|:..|:..|.:..:|...:|||.|::||.||.:|.:||
Zfish   488 FTTSWRNGLAFCALLHHFRPDQIDYKALNPQDIKENNKKAYDGFANLGISRLLEPSDMVLLAIPD 552

  Fly   548 KLAVMTYLHQLRAHFTGKQLKIEQIGSTADESSYVIGDYKSDNLSQNRINFSHPKSLLLHQNSFD 612
            ||.|||||:|:||||:|::|.:.||.:.:..|:|.:||:::|..|.            :.|:.|.
Zfish   553 KLTVMTYLYQIRAHFSGEELNVVQIEANSSRSTYKVGDFETDTNSS------------IDQDKFY 605

  Fly   613 EEIN-------------------GSNKSE----------------------QLSP---TSKKD-- 631
            .|:|                   |:.|.|                      :::|   :||.|
Zfish   606 AELNDIHREPTNQDAAATNGGSDGNEKQEVKSVATAGGSGSLSASPGELLKEVAPSLRSSKADSP 670

  Fly   632 ----VKNLIL---YNSKNILDKVLSPT------------------------KDKNSINAS--QH- 662
                |..|.|   ..::..|:....||                        |:|..:|.|  ||
Zfish   671 AAPSVTELHLRPTQTTRTSLESSRPPTVEQKKLLKADTLDMGDLPHRLEREKEKFEVNDSPEQHE 735

  Fly   663 ----ANQSPMLSCQTT---------------------------PPQDESLDKGSQPG-----GKE 691
                |::|||....::                           ...|.:.|..||..     .|.
Zfish   736 TPRPADRSPMWQTGSSLTNTHKLGFTYNRESDLIKKKRASLRHSESDSTSDSSSQTNHTHIPAKR 800

  Fly   692 NSSITTIDPQAASEE-----RQQRLLEQARRLILETR--------VKSGGSIESPTR-PKL---- 738
            ...:.:......|||     ||:.|.|:||.|:.:.|        .||..:.:|||. |::
Zfish   801 TQEVASAPVSNTSEEKKVLSRQEELKERARLLLEQARRDAAMKAGNKSTNNAQSPTNTPQIIDER 865

  Fly   739 -ERTISPIHNGAEEFYAEHAKKLELKE-PGSPSHRLSDPKVLQSFNAIVERVSPKHEKRGDKLSY 801
             |.....:...|.:..||....:::.| |      |.......:.:|....:..:.:..||.:..
Zfish   866 DEERRRQLRERARQLIAEARSGVKMAELP------LYTDSTSIACSAAGNNLKGRSKTAGDVVDG 924

  Fly   802 ID---------SELEALEREQEAIDQKASNLEAKLRA--VMGGNPSNNRRG----GARNSNPFLR 851
            ::         |::||........|...:|.|.:|.:  :|..:.:|:...    |..||..
Zfish   925 VNVEDEDEEGRSDVEATASASRIDDVTHTNPEEELSSLCLMEDDFTNSATDLAFLGVTNSRH--- 986

  Fly   852 LIRNSIGGGDVIRIKLLDSDDESLFGGGAGSGGGRSGACSEDDDRDTSSD--SVCNSGDELHT-R 913
                       :.:||....:....||.:.|....|.:.:.......|.:  .:.|:.||||. |
Zfish   987 -----------VDLKLKKITEIRPHGGSSPSSSSSSSSLTASSTSPLSPEPGGMQNNVDELHAER 1040

  Fly   914 LR---PRPRSHSCF-----VNKNHQSTINTPAHLRPHHVHHVVPYTHMLDSSPSALSSQ--QSSC 968
            ||   .|.||...|     |.|....:.:.....||.        .....|.|.|:..:  .:..
Zfish  1041 LRRATERLRSPVVFQKESAVRKTQLKSFSQYVETRPE--------VKRQRSVPEAVEERGALTEA 1097

  Fly   969 DNLPACSDDDEVLAVAAN---GRAASLRRQQDRHRRRRQRRERR-SHLCHTPNHCETEETEEQLL 1029
            |......|:.:.....:.   |..|:|..:|.:...|..|.|:| .:|..|.|:   :|.||.::
Zfish  1098 DGRKPTEDEQKAFKDTSQYVVGELAALESEQRQIDTRASRVEKRLRYLMDTGNN---KEEEESMM 1159

  Fly  1030 SQWFTLVNKKNALLRRQMQLNILEQEKDLERKYTMLNQELRAAQSVEDWRKTEVQREKERLLLEE 1094
            .:|||||||||||:|||.||::||:|.||||::.:||:||||..::|||:|||.|:.:|:|||:|
Zfish  1160 QEWFTLVNKKNALIRRQNQLSLLEKEHDLERRFELLNRELRAMLAIEDWQKTEAQKRREQLLLDE 1224

  Fly  1095 LMTIVDKRDQLVQHLHNQE-IAIEDDQEIARKLEH--VDISAEKDKCVLQ 1141
            |:.:|:|||.||:.|..|| .|.|:|:.:.|.||.  ..::.:::|||||
Zfish  1225 LVILVNKRDALVRDLDAQEKEAEEEDEHLERTLEQNKGKMAKKEEKCVLQ 1274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ehbp1	NP_995865.2	NT-C2	12..165	CDD:463058	81/152 (53%)
		CH_EHBP	459..563	CDD:409047	56/103 (54%)
		bMERB_dom	<1027..1122	CDD:463467	54/95 (57%)
ehbp1	XP_005158588.2	None