Protein Alignment Ehbp1 and ehbp1

DIOPT Version :9

• Sequence 1: NP_995865.2
• Gene: Ehbp1 / 36912
• FlyBaseID: FBgn0034180
• Length: 1141
• Species: Drosophila melanogaster
• Sequence 2: XP_005158588.1
• Gene: ehbp1 / 560857
• ZFINID: ZDB-GENE-091006-4
• Length: 1274
• Species: Danio rerio
• Alignment Length: 1352
• Identity: 413/1352 - (30%)
• Similarity: 621/1352 - (45%)
• Gaps: 289/1352 - (21%)

  Fly     1 MASVWKRLQRNFKRAAKFQFTASYHDLHLETTAKWRPSNLSIVWTRRSRRVASAPLPWEPDMMNP 65
            ||||||||||..|.|:||||.|||.::.:|.|.||:|..|.:||||||||.:|....|:|.:.||
Zfish     1 MASVWKRLQRVGKHASKFQFVASYQEIMVECTKKWQPDKLVVVWTRRSRRKSSKSHSWQPGIKNP 65

  Fly    66 LVGNISWPVPDNHTISVTLFKDPRTHELEDKDWTFVIEDVTPMGKKRVLANASINMRKYASIEST 130
            ..|.:.||||:|..|:|||||||...|.|||:||||||:.:|.|:::.||.:.|||::|||...|
Zfish    66 YRGVVVWPVPENIEITVTLFKDPHAEEFEDKEWTFVIENESPSGRRKALATSCINMKQYASAMPT 130

  Fly   131 QQSFTLSLKPVSKKITAASLELTISCVFLREGKATDEDMQSVVSMMSVNNNDVAPLDDLEDIPDL 195
            |....|..||:|||:.:|:|:.::||:||||||||||||||:.|:||:...|:..|||.|:..:.
Zfish   131 QTDVKLKFKPLSKKVVSATLQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEENEE 195

  Fly   196 DGFSEITD-----NFNDFTQQLEHMTTSLNGCIDVATPQS--VPSLSEDPTPLAESFNPLHFELD 253
            |..:.:..     ...:..:||..: :|::|..|....|:  ..|.||:   |....|.|..| |
Zfish   196 DEENRVNQEEKAAKITEIVRQLNAL-SSIDGDPDDCLKQANKAASSSEE---LISKLNFLDQE-D 255

  Fly   254 ADGKREAANKLDLPTAASGGSSGAEESLKTPNGLQHVVDQTPIKSPDEVKQP----KQTPVESLR 314
            .|....:.|..|.|......:...:.....|:...||  |..||..|....|    ::...|...
Zfish   256 QDQSNMSCNPFDEPNDPDDLNPFGDPDEDEPSPQPHV--QPTIKDQDAPDCPFNPFEEADTEPDS 318

  Fly   315 SKTNEDFDKMVTSTPLEPNVN------KDDVKPKKKRALFF--TEKEDEQDLRVESVKEDTTKTI 371
            |:....||:.......:|.|:      :.:|:|.......:  |.:.:|::|. ||......:..
Zfish   319 SQYENPFDEPEPEPEPQPKVSPPRSSKRKNVRPVDMSKYLYANTTRTEEEELD-ESNPFYEPRLS 382

  Fly   372 GDNSTTKEK---------PKEESQSSKDASSVVVPSAKRPE-------LQPLNLKKSYE---PSQ 417
            |.:|:|.||         |......|.......:|....||       |.|..|.....   .|.
Zfish   383 GSDSSTLEKSMKRRAPQPPSAGPNLSVTPGPTPIPKTSSPEGTSTPPALAPSVLTAVIGRELASS 447

  Fly   418 TPESAPVPASVINESIGSCFSTSGSLNNSLKPVEKIVLKENTPGQDLLEWCKEVTKDYPNVKVTN 482
            :|:.:|:|:.|:.....:|.|                         ||.||:||||||..|::||
Zfish   448 SPKPSPIPSPVLGGRPNACSS-------------------------LLAWCREVTKDYRGVRITN 487

  Fly   483 LTTSWRNGMAFCAIIHHFVPELIDMSKLSAHDVVGNCRIGFDAAESLGIPRVIEPRDMNMLTVPD 547
            .|||||||:||||::|||.|:.||...|:..|:..|.:..:|...:|||.|::||.||.:|.:||
Zfish   488 FTTSWRNGLAFCALLHHFRPDQIDYKALNPQDIKENNKKAYDGFANLGISRLLEPSDMVLLAIPD 552

  Fly   548 KLAVMTYLHQLRAHFTGKQLKIEQIGSTADESSYVIGDYKSDNLSQNRINFSHPKSLLLHQNSFD 612
            ||.|||||:|:||||:|::|.:.||.:.:..|:|.:||:::|..|.            :.|:.|.
Zfish   553 KLTVMTYLYQIRAHFSGEELNVVQIEANSSRSTYKVGDFETDTNSS------------IDQDKFY 605

  Fly   613 EEIN-------------------GSNKSE----------------------QLSP---TSKKD-- 631
            .|:|                   |:.|.|                      :::|   :||.|
Zfish   606 AELNDIHREPTNQDAAATNGGSDGNEKQEVKSVATAGGSGSLSASPGELLKEVAPSLRSSKADSP 670

  Fly   632 ----VKNLIL---YNSKNILDKVLSPT------------------------KDKNSINAS--QH- 662
                |..|.|   ..::..|:....||                        |:|..:|.|  ||
Zfish   671 AAPSVTELHLRPTQTTRTSLESSRPPTVEQKKLLKADTLDMGDLPHRLEREKEKFEVNDSPEQHE 735

  Fly   663 ----ANQSPMLSCQT------------TPPQDESLDKGSQPGGKENSSITTIDPQA--------- 702
                |::|||  .||            |..:|..|.|..:...:.:.|.:|.|..:
Zfish   736 TPRPADRSPM--WQTGSSLTNTHKLGFTYNRDSDLIKKKRASLRHSESDSTSDSSSQTNHTHIPA 798

  Fly   703 -------------ASEE-----RQQRLLEQARRLILETR--------VKSGGSIESPTR-PKL-- 738
                         .|||     ||:.|.|:||.|:.:.|        .||..:.:|||. |::
Zfish   799 KRTQEVASAPVSNTSEEKKVLSRQEELKERARLLLEQARRDAAMKAGNKSTNNAQSPTNTPQIID 863

  Fly   739 ---ERTISPIHNGAEEFYAEHAKKLELKE-PGSPSHRLSDPKVLQSFNAIVERVSPKHEKRGDKL 799
               |.....:...|.:..||....:::.| |      |.......:.:|....:..:.:..||.:
Zfish   864 ERDEERRRQLRERARQLIAEARSGVKMAELP------LYTDSTSIACSAAGNNLKGRSKTAGDVV 922

  Fly   800 SYID---------SELEALEREQEAIDQKASNLEAKLRA--VMGGNPSNNRRG----GARNSNPF 849
            ..::         |::||........|...:|.|.:|.:  :|..:.:|:...    |..||..
Zfish   923 DGVNVEDEDEEGRSDVEATASASRIDDVTHTNPEEELSSLCLMEDDFTNSATDLAFLGVTNSRH- 986

  Fly   850 LRLIRNSIGGGDVIRIKLLDSDDESLFGGGAGSGGGRSGACSEDDDRDTSSDS--VCNSGDELHT 912
                         :.:||....:....||.:.|....|.:.:.......|.:|  :.|:.||||.
Zfish   987 -------------VDLKLKKITEIRPHGGSSPSSSSSSSSLTASSTSPLSPESGGMQNNVDELHA 1038

  Fly   913 -RLR---PRPRSHSCF-----VNKNHQSTINTPAHLRPHHVHHVVPYTHMLDSSPSALSSQ--QS 966
             |||   .|.||...|     |.|....:.:.....||.        .....|.|.|:..:  .:
Zfish  1039 ERLRRATERLRSPVVFQKESAVRKTQLKSFSQYVETRPE--------VKRQRSVPEAVEERGALT 1095

  Fly   967 SCDNLPACSDDDEVLAVAAN---GRAASLRRQQDRHRRRRQRRERR-SHLCHTPNHCETEETEEQ 1027
            ..|......|:.:.....:.   |..|:|..:|.:...|..|.|:| .:|..|.|:   :|.||.
Zfish  1096 EADGRKPTEDEQKAFKDTSQYVVGELAALESEQRQIDTRASRVEKRLRYLMDTGNN---KEEEES 1157

  Fly  1028 LLSQWFTLVNKKNALLRRQMQLNILEQEKDLERKYTMLNQELRAAQSVEDWRKTEVQREKERLLL 1092
            ::.:|||||||||||:|||.||::||:|.||||::.:||:||||..::|||:|||.|:.:|:|||
Zfish  1158 MMQEWFTLVNKKNALIRRQNQLSLLEKEHDLERRFELLNRELRAMLAIEDWQKTEAQKRREQLLL 1222

  Fly  1093 EELMTIVDKRDQLVQHLHNQE-IAIEDDQEIARKLEH--VDISAEKDKCVLQ 1141
            :||:.:|:|||.||:.|..|| .|.|:|:.:.|.||.  ..::.:::|||||
Zfish  1223 DELVILVNKRDALVRDLDAQEKEAEEEDEHLERTLEQNKGKMAKKEEKCVLQ 1274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ehbp1	NP_995865.2	NT-C2	12..165	CDD:287345	80/152 (53%)
		CH	460..562	CDD:237981	55/101 (54%)
		DUF3585	<1027..1122	CDD:288945	54/95 (57%)
ehbp1	XP_005158588.1	NT-C2	12..165	CDD:287345	80/152 (53%)
		CH	469..563	CDD:278723	52/93 (56%)
		DUF3585	1113..1239	CDD:288945	62/128 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583248
Domainoid	1	1.000	178	1.000	Domainoid score	I3514
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45597
OrthoDB	1	1.010	-	-		D165311at2759
OrthoFinder	1	1.000	-	-		FOG0002603
OrthoInspector	1	1.000	-	-		otm24810
orthoMCL	1	0.900	-	-		OOG6_105456
Panther	1	1.100	-	-	LDO	PTHR23167
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3165
SonicParanoid	1	1.000	-	-		X2427
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.890