DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ehbp1 and smtnl

DIOPT Version :9

Sequence 1:	NP_995865.2	Gene:	Ehbp1 / 36912	FlyBaseID:	FBgn0034180	Length:	1141	Species:	Drosophila melanogaster
Sequence 2:	NP_997970.1	Gene:	smtnl / 399690	ZFINID:	ZDB-GENE-040212-1	Length:	493	Species:	Danio rerio

Alignment Length:	396	Identity:	101/396 - (25%)
Similarity:	153/396 - (38%)	Gaps:	91/396 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   208 FTQQLEHMTTSLNGCIDVATPQSVPSLSEDPTPLAESFNPLHFELDADGKREAANKLDLPTAASG 272
            |:.:.....||....|:...|..|     ||.|:.:...        :|...:.....:|...:.
Zfish   142 FSSRATFSVTSKTNSIERDEPIEV-----DPAPIPQGLE--------NGHLSSTENSIVPLRRNS 193

  Fly   273 GSSGA--EESLKTPNGLQH--------VVDQTPIKSPDEVKQPKQTPVESLRSKTNEDFDKMVTS 327
            ..:|.  |.|...|..:.|        |.|.|.:|||:....|.|....::.       |.:.:|
Zfish   194 PPNGVLHEHSAPVPMAMPHLPITATTKVADSTVMKSPESPSSPMQATPSAIT-------DSLTSS 251

  Fly   328 TPLEPNVNKDDVKPKKKRALFFTEKEDEQDLRVESVK---EDTTKTIGDNSTTKEKPKEESQSSK 389
            .|:     ..|.:|:.:..:.          .|.|||   ....:|:|....|      |..||.
Zfish   252 PPV-----TSDNQPQLESPVH----------AVSSVKTWAPTPARTMGSPRLT------EKASSA 295

  Fly   390 DASSVVVPSAKRPELQPLNLKKSYEPSQTP----------------ESAPVPASVINESIGSCFS 438
            .|.||....     |.|.|..::.:   ||                .|..:|.::..::..|.|.
Zfish   296 PAKSVTYSG-----LFPHNTDRNVD---TPGDLSFGRGIERRRELVRSQTLPRNIGAQARRSIFE 352

  Fly   439 TSGSLNNSL-KPVE-KIVLKE---------NTPGQDLLEWCKEVTKDYPNVKVTNLTTSWRNGMA 492
            ...|.|||. |||: |..||.         ::..|.|||||:..|..|.|:.:.|.::||.:|||
Zfish   353 RLDSENNSRPKPVDSKPKLKRSQSFGVSSASSIKQILLEWCRSKTIGYQNIDIQNFSSSWSDGMA 417

  Fly   493 FCAIIHHFVPELIDMSKLSAHDVVGNCRIGFDAAE-SLGIPRVIEPRDMNML-TVPDKLAVMTYL 555
            |||::|.|.|...|.:.|:..:...|..:.|..|| ..|..|:||..||.:: ..||.:.|.||:
Zfish   418 FCALVHSFFPTEFDYNGLTPAERKHNFELAFSTAEKKAGCDRLIEVEDMMVMGRKPDPMCVFTYV 482

  Fly   556 HQLRAH 561
            ..|..|
Zfish   483 QSLYNH 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ehbp1	NP_995865.2	NT-C2	12..165	CDD:287345
		CH	460..562	CDD:237981	40/104 (38%)
		DUF3585	<1027..1122	CDD:288945
smtnl	NP_997970.1	TolA_bind_tri	51..>90	CDD:292947
smtnl	NP_997970.1	CH	386..490	CDD:237981	40/103 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910