DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ehbp1 and smtna

DIOPT Version :9

Sequence 1:	NP_995865.2	Gene:	Ehbp1 / 36912	FlyBaseID:	FBgn0034180	Length:	1141	Species:	Drosophila melanogaster
Sequence 2:	XP_003199343.1	Gene:	smtna / 100333230	ZFINID:	ZDB-GENE-091204-245	Length:	271	Species:	Danio rerio

Alignment Length:	248	Identity:	62/248 - (25%)
Similarity:	109/248 - (43%)	Gaps:	38/248 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   322 DKMVTSTPLEPNVNKDDVKP---------KKKRALFFTEKED-EQDLRVESVKEDTTKTIGDNST 376
            |:.:.:..|:..|:.::.|.         |:||     |:.| |:..|:|::::.|.   |..|.
Zfish    32 DEEILNNMLDKAVDFEERKMIRAAMRELLKRKR-----ERRDRERAARMENLRQGTG---GKTSA 88

  Fly   377 TKEKPKEESQSSKDASSVVVPSAKRPEL-QPLNLKKSYEPSQTPESAPVPASVINESIGSCFSTS 440
            :..|.::.|.....|......:|:...| ||.::.     |....|:|..:.|....:....:..
Zfish    89 SLSKDQKASNGPGGAQFNAHRTAQAKTLSQPTSVS-----SPKTVSSPAQSHVARVKMSGGSAVG 148

  Fly   441 GSLNNSLKPVEKIVLKENTPGQDLLEWCKEVTKDYPNVKVTNLTTSWRNGMAFCAIIHHFVPELI 505
            |.....:|             |.||:||:..|:.|..|.:.|.::||.:|:||||::|.|.||..
Zfish   149 GPNTKDVK-------------QMLLDWCRVKTEPYEGVNIQNFSSSWADGLAFCALVHRFFPEGF 200

  Fly   506 DMSKLSAHDVVGNCRIGFDAAESLG-IPRVIEPRDMNMLTVPDKLAVMTYLHQ 557
            :...|:.:|...|....|..||.|. .|.:::..|:..:..||...|.||:.:
Zfish   201 EYCTLNPYDRKSNFEKAFKTAERLADCPPLLDVDDLMRMREPDWKCVYTYIQE 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ehbp1	NP_995865.2	NT-C2	12..165	CDD:287345
		CH	460..562	CDD:237981	34/99 (34%)
		DUF3585	<1027..1122	CDD:288945
smtna	XP_003199343.1	Smoothelin	20..59	CDD:315226	4/26 (15%)
smtna	XP_003199343.1	CH	153..256	CDD:306753	35/114 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910