Protein Alignment CG6805 and SYNJ1

DIOPT Version :10

• Sequence 1: NP_611178.1
• Gene: CG6805 / 36911
• FlyBaseID: FBgn0034179
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_003886.3
• Gene: SYNJ1 / 8867
• HGNCID: 11503
• Length: 1612
• Species: Homo sapiens
• Alignment Length: 351
• Identity: 114/351 - (32%)
• Similarity: 179/351 - (50%)
• Gaps: 66/351 - (18%)

  Fly    16 TWNVG------THTPRNQDLSSLL----SLNGTTTCPD--NQLPDIYVIGFQEV----------- 57
            ||||.      :...:||.|:..|    .|.|.....|  ::..||:.|||:|:
Human   578 TWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVSA 642

  Fly    58 STTPQVLKIFNDDPWVLKIADSLS-DHQFVKVDSKQLQGILITMFAQHKHIPHMKEIETEATRTG 121
            |||.|.|       |.:::..::| |:::|.:.|:||.|:.:.:|.:.:|.|.::::..:..:||
Human   643 STTNQKL-------WAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTG 700

  Fly   122 LGGLWGNKGAVSIRLSLYGTGVAFVCSHLAAHDEKLKERIEDYHQIVDNHKYNAQGYRRIFDHDF 186
            :||..||||||:||:..:.|.:.|||||.||...::|||.||:.:|.  .|.:....|.:|.||:
Human   701 MGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIA--RKLSFPMGRMLFSHDY 763

  Fly   187 VFWFGDLNFRLSGDMSAWDVRTDVENQRYADLLKLDQLNLLREKGNAFSLLEEQQPNFAPTFKFV 251
            |||.||.|:|:  |:...:|:..:..|.:..|:..|||...:..|..|....|.:..||||:|:.
Human   764 VFWCGDFNYRI--DLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYD 826

  Fly   252 EGTNDYNLK---RRPAWCDRILHRVQSNIYPGITLSANQL-----SYQ--SHMDYT--------- 297
            ..::||:..   |.|||.||:|.|.:.  :| ...||..|     |:|  |.:.||
Human   827 LFSDDYDTSEKCRTPAWTDRVLWRRRK--WP-FDRSAEDLDLLNASFQDESKILYTWTPGTLLHY 888

  Fly   298 ------LSDHKPVSATFN---YKVEA 314
                  .|||:||.|..:   ::|||
Human   889 GRAELKTSDHRPVVALIDIDIFEVEA 914

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6805	NP_611178.1	EEP	12..308	CDD:469791	111/340 (33%)
SYNJ1	NP_003886.3	COG5329	73..519	CDD:227637
		INPP5c_Synj1	572..907	CDD:197332	111/342 (32%)
		DUF1866	906..1047	CDD:286093	3/9 (33%)
		Atrophin-1	1049..>1426	CDD:460830