DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6805 and INP52

DIOPT Version :9

Sequence 1:	NP_611178.1	Gene:	CG6805 / 36911	FlyBaseID:	FBgn0034179	Length:	357	Species:	Drosophila melanogaster
Sequence 2:	NP_014293.1	Gene:	INP52 / 855618	SGDID:	S000005050	Length:	1183	Species:	Saccharomyces cerevisiae

Alignment Length:	334	Identity:	109/334 - (32%)
Similarity:	173/334 - (51%)	Gaps:	43/334 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 TAIADLCIFLLTWNVGTHTPRNQDLSSLLSLNGTTTCPDNQLPDIYVIGFQEV--STTPQVLKIF 67
            |..:::.:|:.|:||..:: |..|||..|...|     |...||:.|:|.|||  .|...:|
Yeast   586 TTHSNINLFVGTFNVNGNS-RRADLSKWLFPIG-----DKFKPDVVVLGLQEVIELTAGSIL--- 641

  Fly    68 NDDP-----WVLKIADSLSDHQ--FVKVDSKQLQGILITMFAQHKHIPHMKEIETEATRTGLGGL 125
            |.|.     |...:.|.|:.::  ::.:..:|:..:||..||:.....::||:.....:||.||:
Yeast   642 NADYTKSSFWETMVTDCLNQYEEKYLLLRVEQMSSLLILFFARSDRAYNIKEVGGSTKKTGFGGI 706

  Fly   126 WGNKGAVSIRLSLYGTGVAFVCSHLAAHDEKLKERIEDYHQIVDNHKYNAQGYRRIFDHDFVFWF 190
            .||||||:||.....|...||.:||:|....:.||..||:.|..|..:...  :.|..||.:||.
Yeast   707 TGNKGAVAIRFDYGATSFCFVNTHLSAGASNIDERRNDYNNIYRNITFPRS--KTIPHHDSLFWL 769

  Fly   191 GDLNFRLSGDMSAWDVRTDVENQR--YAD-LLKLDQLNLLREKGNAFSLLEEQQPNFAPTFKFVE 252
            ||||:|::  ::..:||.::..|:  |.| ||:.|||.....:|..|...:|....|.||:|:..
Yeast   770 GDLNYRIT--LTNDEVRRELRAQKDGYIDRLLQYDQLTQEINEGVVFQGFKEPTLQFRPTYKYDY 832

  Fly   253 GTNDYNLK---RRPAWCDRILHRVQSNIYPGITLSANQLSYQSHMDYTLSDHKPVSATFNYKVEA 314
            ||::|:..   |.|:|.|||:::.: |::|        |:| |.....:||||||.|.:.
Yeast   833 GTDNYDTSEKARTPSWTDRIIYKGE-NLHP--------LAY-SDAPLKISDHKPVYAAYR----- 882

  Fly   315 ANQTYTDEE 323
            ||..:.||:
Yeast   883 ANVKFVDEK 891

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6805	NP_611178.1	EEP	12..308	CDD:294334	104/310 (34%)
INP52	NP_014293.1	COG5329	1..628	CDD:227637	15/47 (32%)
		COG5411	564..1052	CDD:227698	109/334 (33%)
		Aim21	<978..1166	CDD:371558
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5411
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810