DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6805 and INP51

DIOPT Version :9

Sequence 1:	NP_611178.1	Gene:	CG6805 / 36911	FlyBaseID:	FBgn0034179	Length:	357	Species:	Drosophila melanogaster
Sequence 2:	NP_012264.3	Gene:	INP51 / 854815	SGDID:	S000001264	Length:	946	Species:	Saccharomyces cerevisiae

Alignment Length:	331	Identity:	111/331 - (33%)
Similarity:	166/331 - (50%)	Gaps:	42/331 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 DLCIFLLTWNVGTHTPRNQDLSSLLSLNGTTTCPDNQLPDIYVIGFQEV---------STTPQVL 64
            |:.||..|:|:....|:: |:...:.....:  .::::.|:||||.:||         :|.|.|.
Yeast   526 DISIFAGTFNISGKIPKD-DIKDWIFPKSMS--KEDEMADLYVIGLEEVVELTPGHMLATDPYVR 587

  Fly    65 KIFNDDPWVLKIADSLS----DHQFVKVDSKQLQGILITMFAQHKHIPHMKEIETEATRTGLGGL 125
            :.     |..||...|:    ..:::::.|.||.|||:.:|........:|.||.:..:||.||:
Yeast   588 QF-----WEKKILTLLNGPGRKKKYIRLWSTQLGGILLLLFMNETEYSKVKHIEGDVKKTGFGGM 647

  Fly   126 WGNKGAVSIRLSLYGTGVAFVCSHLAAHDEKLKERIEDYHQIVDNHKYNAQGYRRIFDHDFVFWF 190
            ..|||||::......|....:.|||||..|.:::|..||..|..:.:: ::|. ||.|||.:.|.
Yeast   648 ASNKGAVAVSFKYSATRFCVLVSHLAAGLENVEQRHNDYKTIAKSIRF-SKGL-RIKDHDAIIWM 710

  Fly   191 GDLNFRLSGDMSAWDVRTDVENQRYADLLKLDQLNLLREKGNAFSLLEEQQPNFAPTFKFVEGTN 255
            ||.|:|:.  ||..|||..:.::.||.|.:.||||.....|.:|....|...:|.||:||..||.
Yeast   711 GDFNYRIL--MSNEDVRRKIVSKEYASLFEKDQLNQQMIAGESFPYFHEMAIDFPPTYKFDPGTK 773

  Fly   256 DYNLK---RRPAWCDRILHRVQSNIYPGITLSANQLSYQSHMDYTLSDHKPVSATFNYKVEAANQ 317
            :|:..   |.|||.||||.|       |..|  .||.|:...|...|||:||.|.|..:|
Yeast   774 NYDTSEKMRIPAWTDRILSR-------GEVL--EQLEYKCCEDILFSDHRPVYAIFRARV----- 824

  Fly   318 TYTDEE 323
            |..||:
Yeast   825 TVVDEQ 830

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6805	NP_611178.1	EEP	12..308	CDD:294334	105/311 (34%)
INP51	NP_012264.3	COG5329	1..501	CDD:227637
INP51	NP_012264.3	COG5411	498..946	CDD:227698	111/331 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5411
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810