DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6805 and inpp5j

DIOPT Version :9

Sequence 1:	NP_611178.1	Gene:	CG6805 / 36911	FlyBaseID:	FBgn0034179	Length:	357	Species:	Drosophila melanogaster
Sequence 2:	XP_002934320.2	Gene:	inpp5j / 779554	XenbaseID:	XB-GENE-984978	Length:	787	Species:	Xenopus tropicalis

Alignment Length:	320	Identity:	130/320 - (40%)
Similarity:	186/320 - (58%)	Gaps:	28/320 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 DLCIFLLTWNVGTHTPRNQDLSSLLSLNGTTTCPDNQLPDIYVIGFQEVSTTPQVLKIFND---- 69
            |..|:::|||||...|.: ||:|||.||..    |::: |::|||.|||::  .:.|...|
Frog   202 DFRIYVITWNVGCAVPPS-DLTSLLCLNAR----DDKI-DMFVIGLQEVNS--MINKRLKDALFS 258

  Fly    70 DPWVLKIADSLSDHQFVKVDSKQLQGILITMFAQHKHIPHMKEIETEATRTGLGGLWGNKGAVSI 134
            |.|.....|.||...:|.|.|.::||.|:.:|:::.|:|.:::|:|:.|||||||.|||||.|||
Frog   259 DQWSEVFMDVLSPFSYVLVSSVRMQGCLLLVFSKYFHLPFLRDIQTDCTRTGLGGYWGNKGGVSI 323

  Fly   135 RLSLYGTGVAFVCSHLAAHDEKLKERIEDYHQIVDNHKYNAQGYRRIFDHDFVFWFGDLNFRLSG 199
            ||||:|..|.|:..||.||.|...:|::::..|:...::.......:.|||.||||||||||:.
Frog   324 RLSLFGHMVCFLNCHLPAHMENTDQRVDNFESILQLQQFQGPLANGVLDHDLVFWFGDLNFRIE- 387

  Fly   200 DMSAWDVRTDVENQRYADLLKLDQLNLLREKGNAFSLLEEQQPNFAPTFKFVEGTNDYNL---KR 261
            |:....|::.::..:.|.|.:.||||:.:......:...|....|.||:||..|||.|:.   ||
Frog   388 DLDLHFVKSAIQGNKLALLWEKDQLNMAKIFEPVLNGFMEGSLTFPPTYKFDVGTNTYDTSSKKR 452

  Fly   262 RPAWCDRILHRVQSNIYPGIT------------LSANQLSYQSHMDYTLSDHKPVSATFN 309
            :|||.||||.:::..|.....            ||...|||.|||.||.||||||||.|:
Frog   453 KPAWTDRILWKMKCPITQSPAKQLGTISTRSKELSVTLLSYGSHMQYTESDHKPVSAIFS 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6805	NP_611178.1	EEP	12..308	CDD:294334	128/314 (41%)
inpp5j	XP_002934320.2	INPP5c_INPP5J-like	203..513	CDD:197328	129/319 (40%)
		SKICH	524..625	CDD:407623
		Abhydrolase	652..>749	CDD:419691
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D336369at33208
OrthoFinder	1	1.000	-	-		FOG0001973
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5114
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.040