Protein Alignment CG6805 and INPP5E

DIOPT Version :10

• Sequence 1: NP_611178.1
• Gene: CG6805 / 36911
• FlyBaseID: FBgn0034179
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_063945.2
• Gene: INPP5E / 56623
• HGNCID: 21474
• Length: 644
• Species: Homo sapiens
• Alignment Length: 352
• Identity: 97/352 - (27%)
• Similarity: 147/352 - (41%)
• Gaps: 70/352 - (19%)

  Fly     9 DLCIFLLTWNVGTHTPRNQDLSSLLSLNGTTTCPDNQLP-------DIYVIGFQEVSTTPQVLKI 66
            ::.:|:.|||:.........|...|            ||       |:||||.||..:..:
Human   298 NVALFVATWNMQGQKELPPSLDEFL------------LPAEADYAQDLYVIGVQEGCSDRR---- 346

  Fly    67 FNDDPWVLKIADSLSDHQFVKVDSKQLQGIL-ITMFAQHKHIPHMKEIETEATRTGLGGLWGNKG 130
                .|..::.::|..|..:.  |....|:| :::|.:...|....|:|.....|.:......||
Human   347 ----EWETRLQETLGPHYVLL--SSAAHGVLYMSLFIRRDLIWFCSEVECSTVTTRIVSQIKTKG 405

  Fly   131 AVSIRLSLYGTGVAFVCSHLAAHDEKLKERIEDYHQIV----------DNHKYNAQGYRRIFDHD 185
            |:.|..:.:||...|:.||..:.|.|:.||:.||.:.|          |.:.|.:.........|
Human   406 ALGISFTFFGTSFLFITSHFTSGDGKVAERLLDYTRTVQALVLPRNVPDTNPYRSSAADVTTRFD 470

  Fly   186 FVFWFGDLNFRLSGDMSAWD------VRTDVENQRYADLLKLDQLNLLREKGNAFSLLEEQQPNF 244
            .||||||.||||||..:..|      :..||     ..||:.|||.....||:.|...:|...:|
Human   471 EVFWFGDFNFRLSGGRTVVDALLCQGLVVDV-----PALLQHDQLIREMRKGSIFKGFQEPDIHF 530

  Fly   245 APTFKFVEGTNDY---NLKRRPAWCDRILHRV--QSNIYPGITLSANQLSYQSHMDYTLSDHKPV 304
            .|::||..|.:.|   :.:|.|::.||:|:|.  :.:|.|        :||.|......|||:||
Human   531 LPSYKFDIGKDTYDSTSKQRTPSYTDRVLYRSRHKGDICP--------VSYSSCPGIKTSDHRPV 587

  Fly   305 SATFNYKVEAANQTYT------DEELH 325
            ...|..||........      |.||:
Human   588 YGLFRVKVRPGRDNIPLAAGKFDRELY 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6805	NP_611178.1	EEP	12..308	CDD:469791	91/324 (28%)
INPP5E	NP_063945.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..193
		PHA03247	<2..179	CDD:223021
		13 X 4 AA repeats of P-X-X-P	10..242
		INPP5c_INPP5E-like	295..593	CDD:197329	92/329 (28%)