Protein Alignment CG6805 and INPPL1

DIOPT Version :10

• Sequence 1: NP_611178.1
• Gene: CG6805 / 36911
• FlyBaseID: FBgn0034179
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001427363.1
• Gene: INPPL1 / 3636
• HGNCID: 6080
• Length: 1280
• Species: Homo sapiens
• Alignment Length: 364
• Identity: 108/364 - (29%)
• Similarity: 166/364 - (45%)
• Gaps: 66/364 - (18%)

  Fly    10 LCIFLLTWNVGTHTPRNQDLSSLLSLNG--------TTTCPDNQLPDIYVIGFQEVSTTPQVLKI 66
            :.:|:.|||:|: .|..::::|..:..|        |.|.|.    ||||.|.||.|.
Human   446 ISVFIGTWNMGS-VPPPKNVTSWFTSKGLGKTLDEVTVTIPH----DIYVFGTQENSV------- 498

  Fly    67 FNDDPWV------LKIADSLSDHQFVKVDSKQLQGILITMFAQHKHIPHMKEIETEATRTGLGGL 125
             .|..|:      ||   .|:|..:..:..:.|..|.:.:..:.:|...:..:.|.:.:||:...
Human   499 -GDREWLDLLRGGLK---ELTDLDYRPIAMQSLWNIKVAVLVKPEHENRISHVSTSSVKTGIANT 559

  Fly   126 WGNKGAVSIRLSLYGTGVAFVCSHLAAHDEKLKERIEDYHQI-----VDNHKYNAQGYRRIFDHD 185
            .||||||.:.....||...||..||.:.:||...|.::|..|     :.:.:.||......|.|
Human   560 LGNKGAVGVSFMFNGTSFGFVNCHLTSGNEKTARRNQNYLDILRLLSLGDRQLNAFDISLRFTH- 623

  Fly   186 FVFWFGDLNFRLSGDMSAWDVRTDVENQRYADLLKLDQLNLLREKGNAFSLLEEQQPNFAPTFKF 250
             :|||||||:||  ||...::...:..:.:..||::|||||.|||...|....|::.:|.||:::
Human   624 -LFWFGDLNYRL--DMDIQEILNYISRKEFEPLLRVDQLNLEREKHKVFLRFSEEEISFPPTYRY 685

  Fly   251 VEGTND-YNLKRR---------PAWCDRILHRVQSNIYPGITLSANQLSYQSHMDYTLSDHKPVS 305
            ..|:.| |...::         |:||||||.:    .||...:..|  ||....|...|||.||.
Human   686 ERGSRDTYAWHKQKPTGVRTNVPSWCDRILWK----SYPETHIICN--SYGCTDDIVTSDHSPVF 744

  Fly   306 ATFNYKV-----------EAANQTYTDEELHEMTHGSAS 333
            .||...|           :.::|.|.:.|..|....:||
Human   745 GTFEVGVTSQFISKKGLSKTSDQAYIEFESIEAIVKTAS 783

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6805	NP_611178.1	EEP	12..308	CDD:469791	99/324 (31%)
INPPL1	NP_001427363.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	919..1140
		SH3-binding	966..971
		NPXY motif	1005..1008