DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6805 and Ocrl

DIOPT Version :9

Sequence 1:	NP_611178.1	Gene:	CG6805 / 36911	FlyBaseID:	FBgn0034179	Length:	357	Species:	Drosophila melanogaster
Sequence 2:	NP_001259153.1	Gene:	Ocrl / 31157	FlyBaseID:	FBgn0023508	Length:	850	Species:	Drosophila melanogaster

Alignment Length:	330	Identity:	110/330 - (33%)
Similarity:	167/330 - (50%)	Gaps:	49/330 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 DLCIFLLTWNVGTHT--PRNQDLSSLLSLNGTTTCPDNQLPDIYVIGFQEVST-------TPQVL 64
            |:.|:..||||...|  ..|..|.:.|:      |.:.. ||||.||.||:.|       :.||.
  Fly   184 DIIIYCATWNVNNKTCSDSNNPLRAWLA------CSEKP-PDIYAIGLQELDTPTKAMLNSTQVQ 241

  Fly    65 KIFNDDPWVLKIADSL-SDHQFVKVDSKQLQGILITMFAQHKHIPHMKEIETEATRTGLGGLWGN 128
            .|  :..|:.|:.||: .|.::..:.|.:|...::|:..:.:...|:.....::...|:....||
  Fly   242 AI--EKQWIDKMMDSVHPDVEYEILMSHRLVATMLTVIVRKQLRQHIIRCRPKSVARGIFNTLGN 304

  Fly   129 KGAVSIRLSLYGTGVAFVCSHLAAHDEKLKERIEDYHQIVDNHKYNAQGYRRIFDHDFVFWFGDL 193
            ||.|:|.|.|....:.||.||||||...::||.:||:.||:..::: .| |.|.|||.:||.|||
  Fly   305 KGGVAISLQLNEGNICFVNSHLAAHMGYVEERNQDYNAIVEGIRFD-DG-RTISDHDHIFWVGDL 367

  Fly   194 NFRLS--------GDMSAWDVRTDVENQRYADLLKLDQLNLLREKGNAFSLLEEQQPNFAPTFKF 250
            |:|:.        |.:|        :.|.|..||:.|||.....:|..|....|.:..|.||:|:
  Fly   368 NYRIQEPPGQQRPGPLS--------DAQTYELLLQYDQLRQEMRRGKCFEGYTEGEIKFRPTYKY 424

  Fly   251 VEGTNDYN---LKRRPAWCDRILHRVQSNIYPGITLSANQLSYQSHMDYTLSDHKPVSATFNYKV 312
            ..||::|:   .:|.||:|||:|       :.|..:  .||:|.|.|:...||||||.|.|..||
  Fly   425 DPGTDNYDSSEKQRAPAYCDRVL-------WKGTRI--EQLAYNSIMEIRQSDHKPVYAVFQVKV 480

  Fly   313 EAANQ 317
            :..::
  Fly   481 KTRDE 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6805	NP_611178.1	EEP	12..308	CDD:294334	106/316 (34%)
Ocrl	NP_001259153.1	PH-like	23..163	CDD:302622
		INPP5c_INPP5B	185..478	CDD:197327	107/320 (33%)
		RhoGAP_OCRL1	614..823	CDD:239845
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447403
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5411
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D105940at6656
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11200
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850