DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6805 and Inpp5k

DIOPT Version :9

Sequence 1:	NP_611178.1	Gene:	CG6805 / 36911	FlyBaseID:	FBgn0034179	Length:	357	Species:	Drosophila melanogaster
Sequence 2:	NP_001013881.1	Gene:	Inpp5k / 287533	RGDID:	1359130	Length:	446	Species:	Rattus norvegicus

Alignment Length:	314	Identity:	117/314 - (37%)
Similarity:	181/314 - (57%)	Gaps:	22/314 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LCIFLLTWNVGTHTPRNQDLSSLLSLNGTTTCPDNQLPDIYVIGFQEVSTTPQVLKIFND----D 70
            |.|.::||||.:..| ..|||.||.||.    .|..| |||:||.||::.  .::.:.:|    |
  Rat    17 LSIHVVTWNVASAAP-TVDLSDLLQLNN----EDLNL-DIYIIGLQEMNY--GIISLLSDAAFED 73

  Fly    71 PWVLKIADSLSDHQFVKVDSKQLQGILITMFAQHKHIPHMKEIETEATRTGLGGLWGNKGAVSIR 135
            ||.....|.||....||:...::||:|:.:||:::|:|:::.|.|::..|||.|.|||||.::|.
  Rat    74 PWSSFFMDMLSPLNLVKISQVRMQGLLLLVFAKYQHLPYIQIISTKSIPTGLYGYWGNKGGINIC 138

  Fly   136 LSLYGTGVAFVCSHLAAHDEKLKERIEDYHQIVDNHKYNAQGYRRIFDHDFVFWFGDLNFRLSGD 200
            |.|||..|:.|..||..|.....:|:|.:.:|:::..:.......|.|||.:.||||:|||:. |
  Rat   139 LKLYGYYVSIVNCHLPPHMYNNDQRLEHFDRILESLTFEGYDVPNILDHDLILWFGDMNFRIE-D 202

  Fly   201 MSAWDVRTDVENQRYADLLKLDQLNLLREKGNAFSLLEEQQPNFAPTFKFVEGTNDYNL---KRR 262
            .....|:..:..:||.:|.:.|||.:.:::.......:|....|.||:||...:|:|:.   ||:
  Rat   203 FGLLFVQECITKKRYKELWEKDQLFIAKKQDQLLREFQEGPLLFPPTYKFDRHSNNYDTSEKKRK 267

  Fly   263 PAWCDRILHRVQ---SNIYP-GITLSANQLSYQSHMDYTLSDHKPVSATFNYKV 312
            |||.||||.|::   :...| |..|:  |..|.|||.|::||||||:.||:.::
  Rat   268 PAWTDRILWRLKRQPAKANPSGFLLT--QKDYVSHMTYSISDHKPVTGTFDLEL 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6805	NP_611178.1	EEP	12..308	CDD:294334	114/306 (37%)
Inpp5k	NP_001013881.1	EEP	17..317	CDD:294334	117/310 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339863
Domainoid	1	1.000	207	1.000	Domainoid score	I2785
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	213	1.000	Inparanoid score	I3555
OMA	1	1.010	-	-		QHG46410
OrthoDB	1	1.010	-	-		D336369at33208
OrthoFinder	1	1.000	-	-		FOG0001973
OrthoInspector	1	1.000	-	-		mtm9020
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11200
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1469
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	12.010