Protein Alignment CG6805 and INPP5J

DIOPT Version :9

• Sequence 1: NP_611178.1
• Gene: CG6805 / 36911
• FlyBaseID: FBgn0034179
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001271214.1
• Gene: INPP5J / 27124
• HGNCID: 8956
• Length: 1006
• Species: Homo sapiens
• Alignment Length: 317
• Identity: 127/317 - (40%)
• Similarity: 189/317 - (59%)
• Gaps: 33/317 - (10%)

  Fly    12 IFLLTWNVGTHTPRNQDLSSLLSLNGTTTCPDNQLPDIYVIGFQEVSTTPQVLKIFND----DPW 72
            |.::||||||..|.: |::|||.|.|.   .|:...|:..||.|||::  .:.|...|    |.|
Human   425 ITVVTWNVGTAMPPD-DVTSLLHLGGG---DDSDGADMIAIGLQEVNS--MLNKRLKDALFTDQW 483

  Fly    73 VLKIADSLSDHQFVKVDSKQLQGILITMFAQHKHIPHMKEIETEATRTGLGGLWGNKGAVSIRLS 137
            .....|:|....||.|.|.::||:::.:||::.|:|.:::::|:.|||||||.|||||.||:||:
Human   484 SELFMDALGPFNFVLVSSVRMQGVILLLFAKYYHLPFLRDVQTDCTRTGLGGYWGNKGGVSVRLA 548

  Fly   138 LYGTGVAFVCSHLAAHDEKLKERIEDYHQIVDNHKYNAQGYRRIFDHDFVFWFGDLNFRLSGDMS 202
            .:|..:.|:..||.||.:|.::|.:::..|:...::...|.:.|.|||.||||||||||:    .
Human   549 AFGHMLCFLNCHLPAHMDKAEQRKDNFQTILSLQQFQGPGAQGILDHDLVFWFGDLNFRI----E 609

  Fly   203 AWD---VRTDVENQRYADLLKLDQLNLLREKGNAFSLLEEQQPNFAPTFKFVEGTNDYNL---KR 261
            ::|   |:..:::.:...|.:.||||:.:.........:|...||||||||..|||.|:.   ||
Human   610 SYDLHFVKFAIDSDQLHQLWEKDQLNMAKNTWPILKGFQEGPLNFAPTFKFDVGTNKYDTSAKKR 674

  Fly   262 RPAWCDRILHRVQSNIYPG----------ITLSANQLSYQSHMDYTLSDHKPVSATF 308
            :|||.||||.:|::   ||          ..|...|.||:|||:||:||||||:|.|
Human   675 KPAWTDRILWKVKA---PGGGPSPSGRKSHRLQVTQHSYRSHMEYTVSDHKPVAAQF 728

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6805	NP_611178.1	EEP	12..308	CDD:294334	126/315 (40%)
INPP5J	NP_001271214.1	INPP5c_INPP5J-like	423..730	CDD:197328	127/317 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146113
Domainoid	1	1.000	210	1.000	Domainoid score	I2816
eggNOG	1	0.900	-	-		E1_COG5411
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8682
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4413
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D336369at33208
OrthoFinder	1	1.000	-	-		FOG0001973
OrthoInspector	1	1.000	-	-		mtm8545
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11200
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5114
SonicParanoid	1	1.000	-	-		X1469
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.790