DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6805 and INPP5F

DIOPT Version :9

Sequence 1:	NP_611178.1	Gene:	CG6805 / 36911	FlyBaseID:	FBgn0034179	Length:	357	Species:	Drosophila melanogaster
Sequence 2:	NP_055752.1	Gene:	INPP5F / 22876	HGNCID:	17054	Length:	1132	Species:	Homo sapiens

Alignment Length:	110	Identity:	24/110 - (21%)
Similarity:	41/110 - (37%)	Gaps:	34/110 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   259 LKRRPA----------------WCDRILHRVQSNIYPGITLSANQLSYQSHMDYTLSDHKPVSAT 307
            ||:.|:                :|.|.:...|:.:              :|:..|.|..:..|..
Human   937 LKKSPSAGDVHILTGFAKPMDIYCHRFVQDAQNKV--------------THLSETRSVSQQASQE 987

  Fly   308 FNYKVEAANQTYTDEELHEMTHGSASSPATPNVSLSFAFVVFVAV 352
            .|   :..||. ::|...|.|..:.|.|:..:||||.....|::|
Human   988 RN---QMTNQV-SNETQSESTEQTPSRPSQLDVSLSATGPQFLSV 1028

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6805	NP_611178.1	EEP	12..308	CDD:294334	10/64 (16%)
INPP5F	NP_055752.1	Syja_N	50..415	CDD:280532
		hSac2	595..697	CDD:289241
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	846..875
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	923..942		2/4 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	974..1017		11/46 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146105
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930