DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6805 and Synj2

DIOPT Version :9

Sequence 1:	NP_611178.1	Gene:	CG6805 / 36911	FlyBaseID:	FBgn0034179	Length:	357	Species:	Drosophila melanogaster
Sequence 2:	NP_001106824.1	Gene:	Synj2 / 20975	MGIID:	1201671	Length:	1479	Species:	Mus musculus

Alignment Length:	375	Identity:	118/375 - (31%)
Similarity:	177/375 - (47%)	Gaps:	62/375 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 TWNVGTHTPRNQDLSSLL-------------SLNGTTTCPDNQLP-DIYVIGFQEV--------- 57
            ||||   ....|..|:||             .|:|.....|:..| |::.|||:|:
Mouse   536 TWNV---NGGKQFRSNLLGTAELTDWLLDAPQLSGAVDSQDDGSPADVFAIGFEEMVELSAGNIV 597

  Fly    58 --STTPQVLKIFNDDPWVLKIADSLS-DHQFVKVDSKQLQGILITMFAQHKHIPHMKEIETEATR 119
              |||       |...|..::..::| .|:::.:.|.||.|:.:.:|.:..|:|.::::..:..:
Mouse   598 NASTT-------NRKMWGEQLQKAISRSHRYILLTSAQLVGVCLYIFVRPYHVPFIRDVAIDTVK 655

  Fly   120 TGLGGLWGNKGAVSIRLSLYGTGVAFVCSHLAAHDEKLKERIEDYHQIVDNHKYNAQGYRRIFDH 184
            ||:||..||||||.||..|:.|...||||||.|...::|||.|||.:|  .||.:....|.||.|
Mouse   656 TGMGGKAGNKGAVGIRFQLHSTSFCFVCSHLTAGQSQVKERNEDYREI--THKLSFPSGRNIFSH 718

  Fly   185 DFVFWFGDLNFRLSGDMSAWDVRTDVENQRYADLLKLDQLNLLREKGNAFSLLEEQQPNFAPTFK 249
            |:|||.||.|:|:  |::..:|...|:.|.:..|::.|||.|.:..|..|....|...||.||:|
Mouse   719 DYVFWCGDFNYRI--DLTYEEVFYFVKRQDWKKLMEFDQLQLQKSSGKIFKDFHEGAVNFGPTYK 781

  Fly   250 FVEGTNDYNLK---RRPAWCDRILHRVQSNIY-----------------PGI--TLSANQLSYQS 292
            :..|:..|:..   |.|||.||:|...:.:.|                 |.|  |.|...|.|..
Mouse   782 YDVGSAAYDTSDKCRTPAWTDRVLWWRKKHPYDKTAGELNLLDSDLDGDPQIRHTWSPGTLKYYG 846

  Fly   293 HMDYTLSDHKPVSATFNYKVEAANQTYTDEELHEMTHGSASSPATPNVSL 342
            ..:...|||:||.|....:|:..:....:....|::.......||..|:|
Mouse   847 RAELQASDHRPVLAIVEVEVQEVDVGARERVFQEVSSVQGPLDATVVVNL 896

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6805	NP_611178.1	EEP	12..308	CDD:294334	112/339 (33%)
Synj2	NP_001106824.1	Syja_N	61..342	CDD:280532
		EEP	530..861	CDD:294334	111/338 (33%)
		DUF1866	872..1008	CDD:286093	5/25 (20%)
		CEND1	1290..>1405	CDD:292305
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836208
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5411
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740