DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6805 and ocrl-1

DIOPT Version :9

Sequence 1:	NP_611178.1	Gene:	CG6805 / 36911	FlyBaseID:	FBgn0034179	Length:	357	Species:	Drosophila melanogaster
Sequence 2:	NP_001361846.1	Gene:	ocrl-1 / 172822	WormBaseID:	WBGene00007620	Length:	712	Species:	Caenorhabditis elegans

Alignment Length:	387	Identity:	122/387 - (31%)
Similarity:	185/387 - (47%)	Gaps:	59/387 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 DLCIFLLTWNVGTHTPRNQDLSSLLSLNGT--TTCPDNQLPDIYVIGFQEVSTTPQVLKIFND-- 69
            |:.|.:.|:||...:|        ||:..|  :..|:: :.:.|.:|.||:..:.....|.|.
Worm    38 DVKICVSTFNVNGRSP--------LSVFPTWFSQKPED-IAEFYAVGLQEMDLSVGTYIIDNTKK 93

  Fly    70 -DPWVLKIADSL--SDHQFVKVDSKQLQGILITMFAQHKHIPHMKEIETEATRTGLGGL---WGN 128
             :.||..|..||  ...||..|.|.:|.||.:.:|........:.::..:...||:..|   .||
Worm    94 MEGWVDAIHCSLPGGRTQFNVVGSMRLVGIFVIVFQAVNSKVRVSDVNVKYVATGISVLVNKLGN 158

  Fly   129 KGAVSIRLSLYGTGVAFVCSHLAAHDEKLKERIEDYHQIVDNHKY----NAQGYRR--------- 180
            ||..::.:.:..|.|.||.:|.||.:.:|:.|.:|:..|.::..:    ..:|.|.
Worm   159 KGGTAVSMKMNDTWVCFVNAHFAAGNNELERRNQDFRDIYNDMVFYPRSQQEGLRDRPLEVPIMC 223

  Fly   181 IFDHDFVFWFGDLNFRLSGDM---SAWDVRTDVENQRYADLLKLDQLNLLREKGNAFSLLEEQQP 242
            ::|||.||||||||:||:.||   |..:||....:.::||||:..||.....:|..|...||  |
Worm   224 LYDHDVVFWFGDLNYRLNTDMYGISNDEVRRIASSDKFADLLQHCQLREQMARGTVFKDFEE--P 286

  Fly   243 N---FAPTFKFVEGTNDYNLK---RRPAWCDRILHRVQSNIYPGITLSA--NQLSYQSHMDYTLS 299
            :   |.||:|:..|||.::..   |.|||.||||   ....||.:.|.:  ..:|..:   .|:|
Worm   287 STLPFRPTYKYDCGTNTWDTSEKGRVPAWTDRIL---TFKKYPQVGLESIRPMVSIDT---ITIS 345

  Fly   300 DHKPVSATFNYKVE-----AANQTYTDEELHEMTHGSASSPATPNVSLSFAFVVFVAVSYTQ 356
            |||||.|.||.||:     .||..| :|.:.|...  .::...|.|.||...|.|..|:|.:
Worm   346 DHKPVRAMFNLKVKKINESGANNVY-EEAIREADR--RANEELPQVQLSLNEVDFGIVNYLE 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6805	NP_611178.1	EEP	12..308	CDD:294334	104/329 (32%)
ocrl-1	NP_001361846.1	INPP5c	39..356	CDD:197308	105/333 (32%)
ocrl-1	NP_001361846.1	RhoGAP_OCRL1	496..705	CDD:239845
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910