DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6805 and Inpp5e

DIOPT Version :9

Sequence 1:	NP_611178.1	Gene:	CG6805 / 36911	FlyBaseID:	FBgn0034179	Length:	357	Species:	Drosophila melanogaster
Sequence 2:	NP_446084.1	Gene:	Inpp5e / 114089	RGDID:	620478	Length:	648	Species:	Rattus norvegicus

Alignment Length:	347	Identity:	95/347 - (27%)
Similarity:	151/347 - (43%)	Gaps:	60/347 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 DLCIFLLTWNVGTHTPRNQDLSSLLSLNGTTTCPDNQLP-------DIYVIGFQEVSTTPQVLKI 66
            ::.:|:.|||:.........|...|            ||       |:||||.||..:..:
  Rat   302 NMALFVATWNMQGQKELPASLDEFL------------LPTEADYTQDLYVIGVQEGCSDRR---- 350

  Fly    67 FNDDPWVLKIADSLSDHQFVKVDSKQLQGILITMFAQHKHIPHMKEIETEATRTGLGGLWGNKGA 131
                .|..::.::|.. |:|.:.|.....:.:::|.:...|....|:|.....|.:......|||
  Rat   351 ----EWETRLQETLGP-QYVLLSSAAHGVLYMSLFIRRDLIWFCSEVEYSTVTTRIVSQIKTKGA 410

  Fly   132 VSIRLSLYGTGVAFVCSHLAAHDEKLKERIEDYHQIV----------DNHKYNAQGYRRIFDHDF 186
            :.:..:.:||...|:.||..:.|.|:.||:.||::.:          |.:.|.:.........|.
  Rat   411 LGVSFTFFGTSFLFITSHFTSGDGKVAERLLDYNRTIQALALPRNVPDTNPYRSSAGDVTTRFDE 475

  Fly   187 VFWFGDLNFRLSGDMSAWD--VRTDVENQRYADLLKLDQLNLLREKGNAFSLLEEQQPNFAPTFK 249
            ||||||.||||||...|.:  ::.|.|....| ||:.|||....:||:.|...||.:.:|.|::|
  Rat   476 VFWFGDFNFRLSGGRVAVEAFLKQDPEVDVLA-LLQHDQLTREMKKGSIFKGFEEAEIHFLPSYK 539

  Fly   250 FVEGTNDY---NLKRRPAWCDRILH--RVQSNIYPGITLSANQLSYQSHMDYTLSDHKPVSATFN 309
            |..|.:.|   :.:|.|::.||:|:  |.:.:|.|        :.|.|......|||:||...|.
  Rat   540 FDIGKDTYDSTSKQRTPSYTDRVLYKSRHKGDICP--------MKYSSCPGIKTSDHRPVYGLFR 596

  Fly   310 YKVEAANQTYT------DEELH 325
            .||........      |.||:
  Rat   597 VKVRPGRDNIPLAAGKFDRELY 618

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6805	NP_611178.1	EEP	12..308	CDD:294334	89/319 (28%)
Inpp5e	NP_446084.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..64
		4 X 4 AA repeats of P-X-X-P	59..243
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	99..158
		INPP5c_INPP5E-like	299..597	CDD:197329	90/324 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910