DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6805 and inppl1

DIOPT Version :9

Sequence 1:	NP_611178.1	Gene:	CG6805 / 36911	FlyBaseID:	FBgn0034179	Length:	357	Species:	Drosophila melanogaster
Sequence 2:	XP_031753288.1	Gene:	inppl1 / 100485745	XenbaseID:	XB-GENE-1013837	Length:	1280	Species:	Xenopus tropicalis

Alignment Length:	325	Identity:	101/325 - (31%)
Similarity:	155/325 - (47%)	Gaps:	41/325 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LCIFLLTWNVGTHTPRNQDLSSLLSLNGTTTCPDNQ---LP-DIYVIGFQEVSTTPQVLKIFNDD 70
            :.:|:.|||:|: .|..::::|.....|.....|:.   :| ||||.|.||.|        ..|.
Frog   414 ISVFIGTWNMGS-VPPQKNITSWFCSKGLGKTLDDMAVTIPHDIYVFGTQENS--------MGDK 469

  Fly    71 PWV--LK-IADSLSDHQFVKVDSKQLQGILITMFAQHKHIPHMKEIETEATRTGLGGLWGNKGAV 132
            .||  |: :....::.::..|..:.|..|.|.:..:.:|...:..|.|.:.:||:....||||||
Frog   470 EWVDFLRGVLKECTEIEYRPVAMQSLWNIKIVVLVRPEHENRISHISTSSVKTGIANTLGNKGAV 534

  Fly   133 SIRLSLYGTGVAFVCSHLAAHDEKLKERIEDYHQI-----VDNHKYNAQGYRRIFDHDFVFWFGD 192
            .|.....||...||..||.:.:||...|.::|..|     :.:.:.|:......|.|  :|||||
Frog   535 GISFMFNGTSFGFVNCHLTSGNEKTSRRNQNYLDILRLLSLGDKQLNSFDISLRFTH--LFWFGD 597

  Fly   193 LNFRLSGDMSAWDVRTDVENQRYADLLKLDQLNLLREKGNAFSLLEEQQPNFAPTFKFVEGTNDY 257
            ||:||  ||...::...:..:.:..|||:|||||.:||...|....|::..|.||:::..|:.|.
Frog   598 LNYRL--DMDVQEILNFISRKEFDPLLKVDQLNLEKEKNKIFLRFNEEELTFPPTYRYERGSRDT 660

  Fly   258 NLKRR----------PAWCDRILHRVQSNIYPGITLSANQLSYQSHMDYTLSDHKPVSATFNYKV 312
            .:..:          |:||||||.:    .||...:..|  ||....|...|||.||.|:|...|
Frog   661 YVWHKHKPTGVRTNVPSWCDRILWK----CYPETHIICN--SYGCTDDIMTSDHSPVFASFEVGV 719

Fly 313 312
Frog 720 719

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6805	NP_611178.1	EEP	12..308	CDD:294334	99/317 (31%)
inppl1	XP_031753288.1	SH2_SHIP	15..117	CDD:198206
		EEP	414..717	CDD:412407	100/321 (31%)
		SAM_superfamily	1223..1277	CDD:417767
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000