DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment AsnRS-m and NS1

DIOPT Version :9

Sequence 1:	NP_611176.1	Gene:	AsnRS-m / 36909	FlyBaseID:	FBgn0034177	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_001328216.1	Gene:	NS1 / 827443	AraportID:	AT4G17300	Length:	587	Species:	Arabidopsis thaliana

Alignment Length:	500	Identity:	170/500 - (34%)
Similarity:	254/500 - (50%)	Gaps:	57/500 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 RRFYSKSG------RIAQIL-----KTNKPGDSLAIQGWIKNVRRLKNNTFLDINDGSTSSRFQV 58
            :||.||.|      |||::.     ..::.|.||.|.||::.:|...:.||::|||||..|..|.
plant    99 KRFGSKVGEFRKKLRIAEVKGGADEGLSRVGQSLNIMGWVRTLRSQSSVTFIEINDGSCLSNLQC 163

  Fly    59 VVPRTP------ENQHLAPGSVIAAVGKIQVAPNGSFELHANQVE-MLAEGRLQEGYPFSPKQKH 116
            |:....      |:..:..|:.::..|.| ||..|:.:....:|| ::..|.....||.. |::.
plant   164 VMTSDAEGYDQVESGSILTGASVSVQGTI-VASQGTKQKVELKVEKIIVVGECDSSYPIQ-KKRV 226

  Fly   117 PPEYVREHLHLRSRVDFVAAQMRVRHKAQKAIHDYMDDQDFVQINTPLLTTNDCEGAGEVFRVQ- 180
            ..|::|...|||.|.:...|..|||:....|.|.:..:..||.:.:|::|.:|||||||.|.|.
plant   227 SREFLRTKAHLRPRTNTFGAVARVRNTLAYATHKFFQESGFVWVASPIITASDCEGAGEQFCVTT 291

  Fly   181 --PDSQ-------DLLKQMNRPNIPMEQSYFDSKVFLSVSGQLHLEAMTYGLGKTYTLSPAFRAE 236
              |.|.       |.:.:.....|...|.:|....||:|||||:.|.....|...||..|.||||
plant   292 LIPSSHENTDTSIDAIPKTKGGLIDWSQDFFGKPAFLTVSGQLNGETYATALSDVYTFGPTFRAE 356

  Fly   237 NSKSPLHLAEFYMFEAELAHL---EEMEKLAQFIEQMLKSVTNRLLETSGEDLSFCQ-------- 290
            ||.:..|||||:|.|.|||..   ::|.....:::.::|.|    |:...||:.|..
plant   357 NSNTSRHLAEFWMIEPELAFADLDDDMACATAYLQYVVKYV----LDNCKEDMEFFDTWIEKGII 417

  Fly   291 RNSNSNSDLPWLQVPWKIMSYDEALQVLQENKDSLKTPISLNEGFSKDQELFLV--AHCGAPVFV 353
            |..:..::..:||     :.|.:|:::|.:.......|:........:.|.::.  |..|.||.:
plant   418 RRLSDVAEKEFLQ-----LGYTDAIEILLKANKKFDFPVKWGLDLQSEHERYITEEAFGGRPVII 477

  Fly   354 VDWPAQQKPFYMKVSRSNPNRVHALDLLMPAVGELCGGSLRESDPAILKSH-PHLPKDLE---WY 414
            .|:|.:.|.|||: ...:...|.|:|:|:|.:|||.|||.||....:|::. ..|..:.|   ||
plant   478 RDYPKEIKAFYMR-ENDDGKTVAAMDMLVPRIGELIGGSQREERLEVLEARLDELKLNKESYWWY 541

  Fly   415 VDLRKYGGVPTGGFGMGFERYLQLVTGVKNIRDVIPFPRYPHSCK 459
            :|||:||.||..|||:||||.:|.|||:.||||||||||.|.|.:
plant   542 LDLRRYGSVPHAGFGLGFERLVQFVTGIDNIRDVIPFPRTPASAE 586

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AsnRS-m	NP_611176.1	asnC	13..460	CDD:235176	165/485 (34%)
		EcAsnRS_like_N	27..101	CDD:239813	24/80 (30%)
		AsxRS_core	115..456	CDD:238399	130/367 (35%)
NS1	NP_001328216.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	203	1.000	Domainoid score	I841
eggNOG	1	0.900	-	-		E1_COG0017
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H57002
Inparanoid	1	1.050	254	1.000	Inparanoid score	I1010
OMA	1	1.010	-	-		QHG62609
OrthoDB	1	1.010	-	-		D1056670at2759
OrthoFinder	1	1.000	-	-		FOG0002378
OrthoInspector	1	1.000	-	-		otm2511
orthoMCL	1	0.900	-	-		OOG6_101288
Panther	1	1.100	-	-	O	PTHR22594
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1800
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840